Product Name
(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate, min. 98% (S,S)-Ph-BPE-Rh
Certificate of Analysis (COA)
IUPAC Name
(1Z,5Z)-cycloocta-1,5-diene;(2S,5S)-1-2-(2S,5S)-2,5-diphenylphospholan-1-ylethyl-2,5-diphenylphospholane;rhodium;tetrafluoroborate
InChI Key
ZNZBTPZGQIGMKZ-NSSKQOQASA-N
SMILES
B-(F)(F)(F)F.C1/C=C\CC/C=C\C1.C1C@H(P(C@@H(C1)C2=CC=CC=C2)CCP3C@@H(CCC@H3C4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C6.Rh
Technical Notes:
1. Phenyl-BPE exhibits enhanced activity and selectivity over existing members of the BPE ligand family in rhodium catalysed asymmetric hydrogenation.
2. This ligand is highly efficient for the hydrogenation of N-acyl aryl-enamides.
3. Molar substrate/catalyst ratios of up to 100,000/1 are achieved with excellent reactivity and enantioselectivity using commercial grade substrates and solvents.
4. Ligand in the rhodium-catalyzed asymmetric hydroformylation of olefins.
References:
1. Org. Lett., 2003, 5, 1273.
2. Tetrahedron Lett, 2004, 45, 9277.
3. Angew. Chem. Int. Ed., 2005, 44, 5834.
