Solid Phase Extraction (SPE) Solutions for Analytical Laboratories
High-Performance SPE Columns for LC-MS / GC-MS Sample Preparation
Overview
Solid Phase Extraction (SPE) is an essential technique for modern analytical workflows, which is widely used in environmental testing, food safety, pharmaceutical quality control and biological sample cleanup.
J&K Scientific offers a complete line of high-purity SPE columns providing clean extracts, high recovery rates and reliable performance for laboratories worldwide.
Our SPE product line covers a broad range of sorbents including C18, Florisil, Silica, PSA, NH₂, SAX, CN, GCB and polymer-based HLB/MCX/MAX types, suitable for both routine testing and advanced LC-MS/GC-MS analysis.
SPE Cartridge Columns Portfolio
Reversed-Phase Sorbents
- C18 SPE Columns – Ideal for non-polar and moderately polar analytes
Normal-Phase Sorbents
- Florisil SPE Columns – Pesticide residue testing, organic pollutants
Ion Exchange Sorbents
- SAX (Strong Anion Exchange)
- NH₂ (Weak Anion Exchange)
Mixed-Mode Sorbents
- PSA (Primary Secondary Amine) – Removes sugars, acids, lipids
- GCB (Graphitized Carbon Black) – Removes pigments and planar interferences
Polymer-Based Sorbents
- HLB / MCX / MAX – Broad chemical compatibility for complex matrices
→ Explore Solid Phase Extraction (SPE) Cartridge columns Collections
SPE Formats and Specifications
SPE products are available in multiple formats to meet global laboratory demands:
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Cartridges: 1 mL, 3 mL, 6 mL, 12 mL
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Sorbent Mass: 50 mg–1000 mg
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96-Well SPE Plates – For high-throughput automation
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Bulk Sorbents – For OEM or specialized workflow development
Application Areas
Environmental Testing
- Pesticides
- PAHs, PCBs
- Organic pollutants
- EPA-compatible methods (e.g., 3535, 8081, 8082)
Food Safety
- Mycotoxins
- Veterinary drug residues
- Pesticide residues in fruits, vegetables, grains
Pharmaceutical & Biomedical
- Drug impurities
- Plasma/serum cleanup
- Metabolite analysis for LC-MS/MS
Research & Academic Laboratories
- General sample cleanup
- Method development
- Extraction optimization
Key Advantages of Our SPE Columns
- High-purity sorbents (pharmaceutical-grade silica & polymers)
- Excellent batch-to-batch reproducibility
- High recovery and low matrix interference
- Compatible with LC-MS / GC-MS workflows
- Meets global testing standards (EPA, AOAC, ISO, USP)
- Cost-effective alternative to major international brands
How to Select the Right SPE Column?
Choosing the correct sorbent is essential for clean extracts and consistent results.
| Sample Type | Recommended Sorbent | Reasons |
|---|---|---|
| Pesticides | Florisil, C18 | Strong cleanup and high recovery |
| Mycotoxins | HLB, PSA | Removes sugars, acids, pigments |
| Biological | HLB, C18 | Compatible with LC-MS/MS |
| Environmental | C18, NH₂, SAX | Effective cleanup for complex matrices |
Need help selecting the right sorbent? Contact our technical specialists
Technical Resources
- SPE Method Development Guide
- Sorbent Selection Chart
- Downloadable SPE Product Catalog (PDF)
- Application Notes for Food, Pharma & Environment
Looking for reliable SPE columns for your analytical laboratory workflows?
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→ Contact our technical specialists
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J&K Scientific provides global supply coverage with strict ISO 9001 quality control, ensuring consistency and performance for laboratories across North America, Europe, Middle East, Southeast Asia, and South America.
