The Michaelis–Arbuzov reaction (also known simply as the Arbuzov reaction) refers to the transformation where trivalent phosphite esters react with alkyl halides to produce pentavalent alkyl phosphonates. The reaction was first discovered by August Michaelis in 1898 and later thoroughly investigated by Aleksandr Arbuzov. The Michaelis–Arbuzov reaction is one of...

Barton Decarboxylation refers to a radical reaction in which a carboxylic acid is first converted into a thiohydroxamate ester (also known as a Barton ester), and then thermally decomposed in the presence of a radical initiator and a suitable hydrogen donor to yield the decarboxylated product. The reaction is named...

The Favorskii reaction refers to the nucleophilic addition of terminal alkynes to carbonyl compounds in the presence of a basic medium (e.g., anhydrous potassium hydroxide or sodium amide), yielding propargylic alcohols. The reaction is named after Russian chemist Alexei Yevgrafovich Favorskii, who first reported it. The reaction mechanism involves deprotonation...

The Dakin reaction refers to the transformation of ortho- or para-hydroxy aromatic aldehydes or ketones into corresponding phenols under basic conditions using hydrogen peroxide. This reaction was discovered by Henry Drysdale Dakin in 1909, and is named in his honor. It is an efficient method for synthesizing polyhydroxy aromatic compounds....

The acylation reaction, also known as acylation, is a key process in organic chemistry where hydrogen or other groups are replaced by acyl groups. The compound providing the acyl group is referred to as the acylating agent. The reaction can be expressed as: RCOZ + SH → RCOS + HZ...

Aromatic hydrocarbonization reaction is a widely used method in enzyme immobilization technology. It involves alkylating and aromatizing polymers with halogen-substituted aromatic rings or heterocycles, followed by reactions with amino, phenol, or sulfhydryl groups on enzyme molecules under alkaline conditions. Aromatic hydrocarbons, commonly referred to as aromatics, are fundamental components of...