Conventional methods for attaching single-stranded DNA (ssDNA) to IgG antibodies often face several challenges. These include high costs associated with ssDNA modification, low coupling efficiency, complex reaction and purification processes, and difficulties in controlling the stoichiometry between ssDNA and IgG.  Professor Hang Xing from Hunan University developed the "AND Linker”,...

Prof. Xia started to work at Southern University of Science and Technology in 2018 as Chair Professor. And acting as Executive Dean of Grubbs Research Institute in Shenzhen in 2019. His research focuses on the synthesis, reactivity, and applications of organometallic conjugated system in the field of Materials Chemistry and...

What is Carbolong? Carbolong is a new class of multi-functional chain compounds containing multiple alkynyl groups. J&K is proud to exclusively supply Carbolong with following advantages: High activity and good selectivity Carbolong contains two excellent reactivity structure units propargyl alcohol and bialkynl. High efficiency Carbolong is able to achieve a variety...

One-step Multi-functionalization of Aromatic Alkynes Aromatic alkyne allows efficient ortho di-functionalization of the aromatic ring. For example, the aryne precursor Kobayashi can functionalize two groups at the 1,2-position of the benzene ring. Would it be possible to achieve tri-functionalization of aromatic rings by aromatic alkynes? Dr. Yang Li has developed...

Novel chiral phosphite ligands with stable properties, mild reaction conditions, high catalytic yields and enantioselectivity. Chirality is closely related to life phenomena and significantly affects material properties. Our demand for optically active substances has led to rapid progress in the research and development of chiral compounds. Dr. Lailai Wang has...

Vinylboronates and alkylboronates are key components in variegated transformations in all facets of chemical science. IMDN-Tf achieves fluoroalkylation-borylation in one step under mild reaction conditions. IMDN-Tf (Fig. 1), developed by Prof. Yi Pan of Nanjing University, is a trifluoromethylation reagent which can release trifluoromethyl radicals under photocatalytic conditions. In addition, boron...