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Sku CI01938_250_MG
Chem Impex
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Product Information

Product Name
2',3'-Dideoxyuridine
Brand Name
Chem Impex
Product Number
01938
CAS
5983-09-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
65161
IUPAC Name
1-(2R,5S)-5-(hydroxymethyl)oxolan-2-ylpyrimidine-2,4-dione
InChI Key
BTOTXLJHDSNXMW-POYBYMJQSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=CC(=O)NC2=O

Application

2',3'-Dideoxyuridine is widely utilized in research focused on

Antiviral Research: This compound is primarily used in the development of antiviral drugs, particularly for treating HIV and other viral infections. Its ability to inhibit viral replication makes it a valuable tool in pharmaceutical research.

Cancer Treatment: Researchers explore its potential in oncology, as it can interfere with DNA synthesis in cancer cells, offering a pathway for developing targeted cancer therapies.

Biochemical Studies: It serves as a crucial reagent in biochemical assays to study nucleic acid metabolism and the mechanisms of action of various enzymes, aiding in the understanding of cellular processes.

Gene Therapy: The compound is investigated for its role in gene therapy applications, where it can be used to modify genetic material, potentially correcting genetic disorders.

Comparative Studies: Its unique properties allow for comparative studies with other nucleoside analogs, helping researchers understand the differences in efficacy and safety profiles, which is essential for drug development.

References

Human Umbilical Cord Mesenchymal Stem Cells Ameliorated Chronic Unpredictable Mild Stress-Induced Depression and Anxiety by Alleviating Neuroinflammation

Publication Name: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Publication Date: 2025-04-24
DOI: 10.1007/s11481-025-10198-2

Synergetic physical damage and chemical oxidation for highly efficient and residue-free water disinfection

Publication Name: Nature Water
Publication Date: 2024-11-28
DOI: 10.1038/s44221-024-00344-0

Synthesis and biological evaluation of pyrrolidine-functionalized nucleoside analogs

Publication Name: Medicinal Chemistry Research
Publication Date: 2021-02-03
DOI: 10.1007/s00044-021-02700-1

Impact of the 2′- and 3′-Sugar Hydroxyl Moieties on Gas-Phase Nucleoside Structure

Publication Name: Journal of The American Society for Mass Spectrometry
Publication Date: 2019-03-08
DOI: 10.1007/s13361-019-02155-0

Aryl H-phosphonates. 19. New anti-HIV pronucleotide phosphoramidate diesters containing amino- and hydroxypyridine auxiliaries

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2019-02-15
DOI: 10.1016/j.ejmech.2018.12.038