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Sku CI00045_5_G
Chem Impex
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Product Information

Product Name
5-Bromo-2'-deoxyuridine
Brand Name
Chem Impex
Product Number
00045
CAS
59-14-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6035
IUPAC Name
5-bromo-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidine-2,4-dione
InChI Key
WOVKYSAHUYNSMH-RRKCRQDMSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=C(C(=O)NC2=O)Br)CO)O

Application

5-Bromo-2'-deoxyuridine is widely utilized in research focused on:

Cell Proliferation Studies: This compound is commonly used to measure cell proliferation and growth in various cell lines, helping researchers understand cancer biology and the effects of different treatments.

DNA Synthesis Research: It serves as a thymidine analog in DNA synthesis studies, allowing scientists to investigate the mechanisms of DNA replication and repair.

Antiviral Drug Development: The compound is explored in the development of antiviral therapies, particularly for its potential effects on viral replication, making it valuable in virology research.

Labeling of Proliferating Cells: It is used as a labeling agent in flow cytometry and microscopy to identify and track proliferating cells in tissue samples, aiding in cancer research and regenerative medicine.

Gene Therapy Applications: Its role in gene therapy is being studied, particularly in the context of delivering therapeutic genes to target cells, which can enhance treatment efficacy for genetic disorders.

References

Yixinshu attenuates myocardial infarction via SHP1/JAK2/STAT3-mediated regulation of mitochondrial function and apoptosis

Publication Name: Chinese Medicine
Publication Date: 2026-03-04
DOI: 10.1186/s13020-025-01299-4

High-altitude de-acclimatization and long-term immune suppression: the role of Nrf2 in Treg function targeting 3PM

Publication Name: The EPMA journal
Publication Date: 2026-03-04
DOI: 10.1007/s13167-026-00442-x

ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging

Publication Name: Nature Aging
Publication Date: 2026-03-04
DOI: 10.1038/s43587-026-01071-9

Deficiency of exocyst complex component Exoc5 exacerbates the progression of kidney fibrosis

Publication Name: Experimental & Molecular Medicine
Publication Date: 2026-03-04
DOI: 10.1038/s12276-026-01649-8

Deciphering molecular spatiotemporal information of brain cells by chemical labeling

Publication Name: Science China Chemistry
Publication Date: 2026-02-27
DOI: 10.1007/s11426-025-3095-x