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Sku CI00045_5_G
Chem Impex
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Product Information

Product Name
5-Bromo-2'-deoxyuridine
Brand Name
Chem Impex
Product Number
00045
CAS
59-14-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6035
IUPAC Name
5-bromo-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidine-2,4-dione
InChI Key
WOVKYSAHUYNSMH-RRKCRQDMSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=C(C(=O)NC2=O)Br)CO)O

Description

5-Bromo-2'-deoxyuridine is widely utilized in research focused on:

Cell Proliferation Studies: This compound is commonly used to measure cell proliferation and growth in various cell lines, helping researchers understand cancer biology and the effects of different treatments.

DNA Synthesis Research: It serves as a thymidine analog in DNA synthesis studies, allowing scientists to investigate the mechanisms of DNA replication and repair.

Antiviral Drug Development: The compound is explored in the development of antiviral therapies, particularly for its potential effects on viral replication, making it valuable in virology research.

Labeling of Proliferating Cells: It is used as a labeling agent in flow cytometry and microscopy to identify and track proliferating cells in tissue samples, aiding in cancer research and regenerative medicine.

Gene Therapy Applications: Its role in gene therapy is being studied, particularly in the context of delivering therapeutic genes to target cells, which can enhance treatment efficacy for genetic disorders.