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Sku CI00191_100_G
Chem Impex
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Product Information

Product Name
5-Iodo-2'-deoxyuridine
Brand Name
Chem Impex
Product Number
00191
CAS
54-42-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
5905
IUPAC Name
1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl-5-iodopyrimidine-2,4-dione
InChI Key
XQFRJNBWHJMXHO-RRKCRQDMSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=C(C(=O)NC2=O)I)CO)O

Application

5-Iodo-2'-deoxyuridine is widely utilized in research focused on:

Antiviral Research: This compound is effective in studying viral replication, particularly in the development of antiviral therapies against herpes simplex virus and other DNA viruses.

Cancer Treatment: It serves as a nucleoside analog in cancer research, helping to understand its role in inhibiting tumor cell proliferation and enhancing the efficacy of chemotherapy.

Genetic Studies: Researchers use it to explore DNA synthesis and repair mechanisms, providing insights into genetic disorders and potential therapeutic interventions.

Pharmaceutical Development: This compound is a valuable tool in drug formulation, particularly for creating targeted therapies that require precise nucleoside modifications.

Diagnostic Applications: It can be employed in molecular imaging techniques, aiding in the detection and monitoring of certain diseases through its incorporation into DNA.

References Data Source From Pubchem

Antiviral drug discovery and development: challenges and future directions

Publication Name: Signal Transduction and Targeted Therapy
Publication Date: 2026-02-25
DOI: 10.1038/s41392-025-02539-7

Utilizing pH-sensitive nanoparticles in cancer radiotherapy: mechanisms and therapeutic potential

Publication Name: Journal of Nanoparticle Research
Publication Date: 2026-01-28
DOI: 10.1007/s11051-026-06553-w

Oncogenic p53 induces mitotic errors in lung cancer cells by recopying DNA replication forks conferring targetable proliferation advantage

Publication Name: Cell death and differentiation
Publication Date: 2026-01-26
DOI: 10.1038/s41418-026-01670-4

Antiviral Drug Design: Past, Presence, and Future

Publication Name: Advances in experimental medicine and biology
Publication Date: 2026
DOI: 10.1007/978-3-032-03402-1_37