The basic building blocks of biomimetic homopolypeptides are protected or unprotected glutamic acid or lysine residues, which are obtained through ring-opening polymerization of cyclic amino acid anhydrides. They can be used in the field of biomedicine as drug delivery, gene delivery carriers or degradable biomimetic medical materials [1-2]. They can...

Click Chemistry is a synthesis concept proposed by Sharpless, a Nobel Prize winner in chemistry from the United States, in 2001 [1]. Among them, the main and classic click chemical reaction is the Cu(I)-catalyzed azide-alkynyl Husigen cycloaddition reaction (CuAAC). This reaction has the advantages of high yield, few side reactions,...

5-methylcytosine modification (5mC) is one of the important epigenetic modifications in eukaryotic cell genomes. 5mC can be gradually oxidized under the action of TET family enzymes to generate 5-hydroxymethylcytosine (5hmC), 5-aldehydecytosine (5fC) and 5-carboxycytosine (5caC); for the above-mentioned several new DNA modifications Functional research is currently a hot spot in...

Polyamide-amine (PAMAM) polymer materials are a type of highly branched, "all-rounder" dendrimers with specific three-dimensional structures and highly controllable molecular size and configuration. Its unique molecular structure and physical and chemical properties make it widely used in biomedicine sustained release, genetic material carrier, surfactant, environmental pollution treatment, etc. It is...

Professor Zhang Yongqiang of Shandong University has developed a series of (Salen)Ti catalysts. This series of catalysts has a deep chiral environment, excellent enantioselective control, and covers the dual functions of chiral Lewis acids and chiral metal radicals. It can be used in many applications. A variety of chemical transformations...

Polysulfamide is a linear polymer with selective metal (palladium) adsorption capacity. The research group of Professor Yi Wenbin of Nanjing University of Science and Technology has developed a general method for preparing polysulfamide using secondary amines, and uses palladium to assist the synthesis of polysulfamide. A palladium-crosslinked polysulfamide skeleton metal...