Cutting-Edge Mesoporous Materials by Zhao Dongyuan: Revolutionizing Applications in Science and Industry On November 3, 2021, the project "Creation and Application of Ordered Mesoporous Polymers and Carbon Materials" led by Zhao Dongyuan, an academician of the Chinese Academy of Sciences and professor at Fudan University's Department of Chemistry, was awarded...

Innovative Deuterated Methylated Aromatics by Professor Zhou Qianghui: Transforming Medicinal Chemistry Methyl groups are commonly found in small-molecule drugs and play a vital role in enhancing drug properties. Numerous studies demonstrate that introducing methyl groups at specific sites in candidate drugs can: Improve metabolic stability, Shorten half-life, Enhance solubility and...

Mitochondria-Targeted Research with IR-780 Ethyl Iodide Mitochondria are fundamental organelles in eukaryotic cells, playing a crucial role in energy metabolism. Positively charged dyes are commonly used for mitochondrial labeling in living cells, offering innovative methods to study mitochondrial metabolic processes. IR-780 Ethyl Iodide (λex = 780 nm, λem = 830...

Coumarin Compounds: Versatile Fluorescent Chromophores for Advanced Research Coumarin compounds are highly versatile fluorescent and laser dyes with exceptional performance characteristics. As fluorescent chromophores, they have remained a focal point in the research and development of fluorescent probes. These compounds are widely used for synthesizing coumarin derivatives and optical probes...

Hexasubstituted benzene derivatives are a class of compounds with exceptional structural attributes, offering six derivatization sites. These compounds exhibit structural rigidity, high symmetry, abundant modification possibilities, and diverse topological configurations. Their unique properties make them invaluable in constructing functional supramolecular assemblies and dendrimers. Consequently, these derivatives are widely utilized in...

Superfan compounds are a novel class of molecular cages with unique structural features. Composed of two parallel benzene rings connected by six side chains, these compounds form a lantern-like structure with a (quasi-) closed internal cavity and numerous recognition sites distributed around the cavity. Compared to traditional supramolecular host compounds,...