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Sku SC07-7130_50_MG
US-Strem
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Product Information

Product Name
(R)-1-3,5-Bis(trifluoromethyl)phenyl-3-1-(dimethylamino)-3-methylbutan-2-ylthiourea, 98%, (99% ee)
Brand Name
US-Strem
Product Number
07-7130
CAS
1048692-61-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
89493462
IUPAC Name
1-3,5-bis(trifluoromethyl)phenyl-3-(2R)-1-(dimethylamino)-3-methylbutan-2-ylthiourea
InChI Key
KRYYOIQNEMXCQT-ZDUSSCGKSA-N
SMILES
CC(C)C@H(CN(C)C)NC(=S)NC1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Application

Technical Notes:
1.Methanolysis: Both ureas and thioureas derived from L -valine or D-valine act as bifunctional
organocatalysts able to induce the enantioselective alcoholysis of mono-, bi-, and tricyclic meso anhydrides.
References:
1. J. Org. Chem., 2010, 75, 5417-5420.