3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 95%, (99% ee)

Technical Notes:
1.An efficient diastereo- and enantioselective Michael addition of 3-substituted oxindoles onto nitroalkenes catalyzed by a bifunctional chiral squaramide catalyst has been developed.
2.An efficient chiral squaramide catalysed enantiosele ctive Michael addition of pyrazolin-5-ones to
nitroalkenes has been developed.
3.An efficient asymmetric cascade sulfa-Michael/Michael addition reaction catalyzed by a chiral bifunctional squaramide-tertiary amine catalyst has been developed.
4.A highly enantio- and diastereoselective sulfa-Michael addition of thioacetic acid to a,ß-disubstituted nitroalkenes catalysed by a chiral squaramide organocatalyst has been described.