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Sku SC07-1418_100_MG
US-Strem
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Product Information

Product Name
N-(1R,2R)-2-Amino-1,2-diphenylethyl-N'-3,5-bis(trifluoromethyl)phenylthiourea, 98%
Brand Name
US-Strem
Product Number
07-1418
CAS
1088705-53-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
49794471
IUPAC Name
1-(1R,2R)-2-amino-1,2-diphenylethyl-3-3,5-bis(trifluoromethyl)phenylthiourea
InChI Key
IYOXSNQTLZTQFG-WOJBJXKFSA-N
SMILES
C1=CC=C(C=C1)C@H(C@@H(C2=CC=CC=C2)NC(=S)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N

Description

Technical Notes:
1.Catalyst for the asymmetric Michael addition of a, a-disubstituted aldehydes to maleimides .
2.Used in the enantioselective synthesis of trans dihydrobenzofurans via intramolecular Michael addition.
3.Organocatalyst for the enantioselective direct vinylogous aldol reaction of 3-methyl 2-cyclohexen-1-one with a-keto esters.
4.Organocatlyst for enantioselective F riedel-Crafts alkylations of furans.
5.Catalyst for the regio- and diastereodivergent 4+2 cycloadditions with cyclic 2,4-Dienones.

References Data Source From Pubchem

Introduction of Alkyl Groups

Publication Name: Science of Synthesis
Publication Date: 2024

Primary Amine–Thiourea-Catalyzed Enantioselective Alkylation of Cyclic Ketones

Publication Name: Synfacts
Publication Date: 2022-10-18
DOI: 10.1055/s-0041-1738729

Enantioselective Synthesis of β-Nitro Phosphonates Catalyzed by a Secondary Amine Bisthiourea

Publication Name: Synlett
Publication Date: 2018-04-20
DOI: 10.1055/s-0037-1609683

Enantioselective Friedel–Crafts Reaction of Furylacetones

Publication Name: Synfacts
Publication Date: 2014-06-16
DOI: 10.1055/s-0034-1378219