3-[[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee)

Technical Notes:
1.Macheal Addition- highly enantioselective Michael addition reaction of diphenyl phosphite to a range of nitroalkenes .
2.Hydrophosphonylation- diphenylphosphite has been successfully employed in a chiral Pudovik reaction with aldehydes, extending the generality of this asymmetric methodology.
3.Friedel-Crafts/Substitution Domino Reaction- Dihydroarylfuran skeletons are efficiently synthesized from (Z)- bromonitroalkenes and naphthol derivatives in good yields and excellent enantioselectivities
References:
1.Angew. Chem. Int. Ed., 2010, 49, 153-1 56. 2.Org. Biomol. Chem., 2014, 12, 1258-1264.
3.Angew. Chem. Commun., 2013, 49, 2001-2003.