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Sku SC07-1350_50_MG
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Product Information

Product Name
1-3,5-Bis(trifluoromethyl)phenyl-3-(1R,2R)-2-(pyrrolidin-1-yl)cyclohexylthiourea, 98%, (99% ee)
Brand Name
US-Strem
Product Number
07-1350
CAS
1314743-49-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
101547713
IUPAC Name
1-3,5-bis(trifluoromethyl)phenyl-3-(1R,2R)-2-pyrrolidin-1-ylcyclohexylthiourea
InChI Key
BSICYYMKFDEOFB-HZPDHXFCSA-N
SMILES
C1CCC@H(C@@H(C1)NC(=S)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)N3CCCC3

Description

Technical Notes:
1. Michael Addition: A highly diastereoselective and enantioselective Michael addition of a-substituted
isocyanoacetates with maleimides catalyzed by bifunctional tertiary amine thioureas has been developed.
R3
References:
1. J. Org. Chem., 2012. 77, 2947-2953.

References Data Source From Pubchem

N-Halo Reagents: Modern Synthetic Approaches for Heterocyclic Synthesis

Publication Name: Synthesis
Publication Date: 2019-03-27
DOI: 10.1055/s-0037-1611746