Product Name
Oleic acid, 90%
Molecular Formula
C18H34O2
Certificate of Analysis (COA)
Synonyms
cis-9-Octadecenoic acid
IUPAC Name
(Z)-octadec-9-enoic acid
InChI Key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)O
Product Introduction
Oleic Acid (CAS No. 112-80-1) is a naturally occurring monounsaturated fatty acid containing 18 carbon atoms and one cis double bond at the C9 position. It is one of the most abundant fatty acids found in natural oils and fats.
Oleic Acid is widely used in biochemistry, lipid research, cell biology, pharmaceutical research, food science, cosmetic formulation, and materials science. Its amphiphilic structure and biological relevance make it a useful model compound for studying fatty-acid metabolism, lipid signaling, membrane composition, and cellular responses to lipid exposure.
It is also widely used as a formulation ingredient, emulsification aid, surfactant component, and chemical intermediate.
Mechanism / Principle
Fatty Acid and Lipid Function
Oleic Acid functions as a long-chain unsaturated fatty acid and can participate in lipid metabolism and membrane-related processes.
In biological research:
- Oleic Acid can be incorporated into cellular lipid pools.
- It can influence membrane lipid composition and properties.
- It serves as a substrate for enzymes involved in fatty-acid metabolism.
- It can be converted into various oleate-containing lipid species.
- Its addition to cell culture systems can be used to study lipid accumulation and cellular responses.
Its single cis double bond introduces structural flexibility compared with saturated fatty acids, affecting the physical properties of lipid assemblies and biological membranes.
Key Research Applications
1. Cell Biology and Lipid Research
Oleic Acid is widely used to investigate cellular lipid metabolism and lipid accumulation.
Applications include:
- Lipid metabolism studies
- Cellular lipid accumulation
- Lipid droplet research
- Fatty-acid metabolism
- Lipid signaling research
2. Cell Culture Research
Oleic Acid is frequently used in experimental models where researchers need to induce or investigate lipid accumulation.
Applications include:
- Hepatocyte lipid accumulation models
- Adipocyte differentiation studies
- Steatosis-related research
- Metabolic research
- Cellular lipid-response studies
3. Biochemistry and Enzymology
Oleic Acid can serve as a substrate or model fatty acid in biochemical studies.
Applications include:
- Fatty-acid metabolism assays
- Lipase research
- Fatty-acid oxidation studies
- Enzyme-substrate investigations
- Lipid biochemistry
4. Pharmaceutical Research
Oleic Acid is investigated in pharmaceutical and drug-delivery research because of its lipid properties and ability to participate in lipid-based formulations.
Applications include:
- Lipid-based drug delivery
- Nanoparticle formulation
- Liposome research
- Pharmaceutical formulation development
- Bioavailability studies
5. Cosmetic and Personal Care Formulation
Oleic Acid is widely used as an emollient and formulation component.
Applications include:
- Skin-care formulations
- Emulsions
- Creams and lotions
- Emollient systems
- Surfactant formulations
6. Food and Nutritional Research
Oleic Acid is an important dietary monounsaturated fatty acid and is widely studied in nutritional science.
Applications include:
- Fatty-acid profiling
- Nutritional research
- Lipid composition analysis
- Food chemistry
- Oil characterization
7. Materials and Chemical Research
Oleic Acid can also function as a surface-modifying ligand and organic component in materials synthesis.
Applications include:
- Nanoparticle synthesis
- Surface modification
- Colloidal nanomaterials
- Metal oxide nanoparticle stabilization
- Organic materials research
Advantages
- Naturally occurring monounsaturated fatty acid
- Well-defined C18 fatty-acid structure
- Widely used in lipid and cell biology research
- Suitable for cellular lipid accumulation models
- Useful in biochemical and enzymatic studies
- Applicable to lipid-based drug-delivery research
- Useful as a surface ligand in nanomaterial synthesis
- Broad applications in formulation and materials research
Storage & Handling
- Store in a tightly closed container.
- Keep in a cool, dry environment.
- Protect from excessive heat and direct sunlight.
- Minimize prolonged exposure to air to reduce oxidation.
- For sensitive applications, storage under an inert atmosphere may be appropriate.
- Avoid contact with strong oxidizing agents.
- Follow the product-specific SDS and storage specifications.
Research Areas
Researchers working in the following fields may benefit from Oleic Acid (CAS No. 112-80-1):
- Lipid biology
- Cell biology
- Biochemistry
- Metabolic research
- Pharmaceutical research
- Drug delivery
- Nanomaterials
- Food science
- Nutritional research
- Cosmetic formulation
- Materials science
Q1: What is Oleic Acid?
A: Oleic Acid is a monounsaturated fatty acid with the molecular formula C₁₈H₃₄O₂ and CAS No. 112-80-1. It contains one cis double bond at the ninth carbon position.
Q2: What is Oleic Acid used for?
A: Oleic Acid is used in lipid research, cell biology, biochemistry, pharmaceutical formulation, drug delivery, food science, cosmetics, and nanomaterial synthesis.
Q3: What is the molecular weight of Oleic Acid?
A: The molecular weight is 282.46 g/mol.
Q4: Is Oleic Acid a saturated or unsaturated fatty acid?
A: Oleic Acid is a monounsaturated fatty acid containing one cis carbon–carbon double bond.
Q5: Can Oleic Acid be used in cell culture research?
A: Yes. Oleic Acid is commonly used in cellular models investigating lipid accumulation, fatty-acid metabolism, adipocyte biology, and metabolic responses.
Q6: Is Oleic Acid used in nanoparticle synthesis?
A: Yes. Oleic Acid is commonly used as a surface ligand or stabilizing agent in the synthesis and processing of various colloidal nanomaterials.
Q7: What is the physical form of Oleic Acid?
A: Oleic Acid is generally supplied as a liquid at room temperature.
Q8: How should Oleic Acid be stored?
A: Store tightly sealed in a cool, dry environment and minimize exposure to air, heat, and light to help limit oxidation.