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Sku SC07-1355_50_MG
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Product Information

Product Name
3-3,5-Bis(trifluoromethyl)phenylamino-4-(1R,2R)-2-(1-pyrrolidinyl)cyclohexylamino-3-cyclobutene-1,2-dione, 95%, (99% ee)
Brand Name
US-Strem
Product Number
07-1355
CAS
1211565-10-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
73212143
IUPAC Name
3-3,5-bis(trifluoromethyl)anilino-4-(1R,2R)-2-pyrrolidin-1-ylcyclohexylaminocyclobut-3-ene-1,2-dione
InChI Key
CRIYFAISGRLYEW-HZPDHXFCSA-N
SMILES
C1CCC@H(C@@H(C1)NC2=C(C(=O)C2=O)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCCC4

Description

Technical Notes:
1. Michael Addition- An efficient diastereo- and enantioselective addition of a-substituted isocyanoacetates to N-aryI maleimides .
References:
1. Tetrahedron, 2013, 69, 10763-10771.

References Data Source From Pubchem

Asymmetric Michael Reaction of Malononitrile and α,β-Unsaturated Aldehydes Catalyzed by Diarylprolinol Silyl Ether

Publication Name: Synlett
Publication Date: 2022-06-09
DOI: 10.1055/a-1846-5007

Asymmetric Organocatalysis with Masked Acyl Cyanides

Publication Name: Synfacts
Publication Date: 2013-11-18
DOI: 10.1055/s-0033-1340277