Product Added to Cart!
(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee)|07-0956|479423-21-7

(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee)

$165.00

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku SC07-0956_50_MG
US-Strem
Get Bulk Quote

Product Information

Product Name
(2S)-2-(1R,2R)-2-Aminocyclohexylaminothioxomethylamino-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee)
Brand Name
US-Strem
Product Number
07-0956
CAS
479423-21-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
57332980
IUPAC Name
(2S)-2-(1R,2R)-2-aminocyclohexylcarbamothioylamino-N-benzyl-N,3,3-trimethylbutanamide
InChI Key
CNEVMNSDRMDKFO-KZNAEPCWSA-N
SMILES
CC(C)(C)C@@H(C(=O)N(C)CC1=CC=CC=C1)NC(=S)NC@@H2CCCCC@H2N

Description

Technical Notes:
1.Conjugate Addition: Primary amine -thiourea derivative is an active and highly enantioselective catalyst for the conjugate addition of ketones to nitroalkenes.
2.Michael Addition: The asymmetric Michael addition of dioxindoles to ß-substituted nitroalkenes is reported. The bifunctional primary amine-thiourea, by means of a non-covalent-based mode of catalysis, secures
direct access to 3-substituted 3-hydroxyoxindole derivatives with high stereocontrol.
References:
1. J. Am. Chem. Soc., 2006, 128, 7170-7171. 2. Chem. Commun., 2012, 48, 3336-3338.