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Sku SC07-0912_100_MG
US-Strem
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Product Information

Product Name
N-3,5-Bis(trifluoromethyl)phenyl-N'-(2S)-2-pyrrolidinylmethylthiourea, 98%
Brand Name
US-Strem
Product Number
07-0912
CAS
904928-30-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11574269
IUPAC Name
1-3,5-bis(trifluoromethyl)phenyl-3-(2S)-pyrrolidin-2-ylmethylthiourea
InChI Key
ULGQYSSQBVDCSA-JTQLQIEISA-N
SMILES
C1CC@H(NC1)CNC(=S)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F

Description

Technical Notes:
1.Michael Addition: Asymmetric Michael additions of cyclohexanone to both aryl and alkyl nitroolefins in the presence of 20 mol% of organocatalyst and 10 mol% of n-butyric acid afford adducts with high diastereoselectivities and enantioselectivities.
References:
1.Org L ett., 2006, 8, 2901-2904.