The research group led by Professor Fang Yu at Hunan University has successfully developed a novel catalyst, PCC@THF-OOH, which achieves light-dark catalytic coupling. This breakthrough is based on a phenothiazine-based octahedral porous coordination cage (PCC-6-Zn), where the zinc metal center selectively generates singlet oxygen for oxidation reactions under light conditions...
12
Dec
Trifluoromethyldiazomethane (CF₃CHN₂), difluoromethyldiazomethane (CHF₂CHN₂), and formyldiazomethane (CHOCHN₂) are widely used as highly reactive reagents for trifluoromethylation, difluoromethylation, and formylation in the synthesis of organic fluorine compounds and aldehydes. However, these gases are toxic, volatile, and explosive, posing significant safety risks during production, storage, and use. Managing these safety concerns has...
11
Dec
Formyldiazomethane (CHOCHN₂) and difluoromethyldiazomethane (CHF₂CHN₂) are highly reactive, low-molecular-weight compounds widely used to introduce difluoromethyl or aldehyde groups into organic molecules. Despite their value, these functionalized diazomethane derivatives pose significant safety risks due to their gaseous state, volatility, toxicity, and explosiveness under standard conditions. Existing production methods require handling explosive...
11
Dec
Trifluoromethyldiazomethane (CF₃CHN₂) is a crucial precursor for introducing trifluoromethyl groups into organic molecules, widely applied in organic synthesis. Despite its importance, traditional production methods present significant challenges in storage, safety, and handling risks (see Figure 1). To solve these issues, Professor Bi Xihe’s research group at the School of Chemistry,...
11
Dec
In organic synthesis, sulfur dioxide (SO₂) is a crucial reagent, but commonly used SO₂-releasing compounds come with significant limitations: Sodium sulfite (Na₂SO₃): Requires concentrated sulfuric acid, generating excessive heat. Sodium metabisulfite (Na₂S₂O₅) & potassium metabisulfite (K₂S₂O₅): Often demand high temperatures and phase transfer catalysts. Sodium hydroxymethylsulfonate (HOCH₂SO₂Na·2H₂O): Highly hygroscopic, leading...
11
Dec
Organometallic chemistry focuses on the synthesis, structure, reaction, properties and applications of metal-organic compounds, and plays an important role in promoting the development of human society. Metallo-organic compounds are complexes composed of a central metal atom and ligands surrounding the metal atom. Carbonlon is a new type of chain polyyne...
