First row transition metal catalysts show potential as cheaper, more abundant alternatives to their second and third row counterparts. However, catalysis with first-row transition metal systems is frequently hampered by low turnover and sensitivity to catalyst poisoning, often necessitating higher catalyst loadings. Applying first row transition metals to reactions such...

J&K Scientific provides a series of phosphonate rare earth extractants (P227, C272, P507) developed by Professor Xiao Jichang from Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences. Compared with industrial grade (purity of about 90%), high-purity rare earth extractants (purity of 95-99%) are more effective in the separation of...

Alkynylamide condensation reagents (Figure 1) are a type of reagent with a new structure developed by Professor Zhao Junfeng's research group and are used for the direct condensation of acids and amines. They are characterized by moderate activity and can effectively avoid the activation of the α-position chiral center of...

Aromatic alkynes are active intermediates formed by the partial overlap of sp2 orbitals of two carbon atoms ortho to an aromatic ring. This structure can efficiently achieve ortho difunctionalization of aromatic rings. For example, the currently widely used Kobayashi aryne precursor can functionalize two groups at the 1,2-position of the...

Trifluoromethyl is an important structure. Introducing it into organic compounds can improve the polarity, dipole moment, stability, and lipophilicity of the target product. Therefore, compounds containing trifluoromethyl are widely used in medicines and pesticides. , new materials and other fields are of great significance. Methyl fluorosulfonyl difluoroacetate (also known as...

Alkaline phosphatase (ALP) is a hydrolase that is widely present in human liver and bones [1] . The ALP content in human serum is an important indicator for the diagnosis of liver diseases such as liver cancer and bone diseases, and has very important clinical significance [2-3].The precipitation-type ALP fluorescent...