Are You Facing These Challenges?
When conducting antibody-DNA conjugation experiments, do you find yourself constantly worrying—will this batch have stable conjugation efficiency? Has the antibody activity been compromised? Will the data reproducibility pass the scrutiny of reviewers?
Random thiol conjugation, non-site-specific amine labeling... The processes are tedious, the efficiency is low, and the resulting products are heterogeneous.
Choose the Same Tool Used in Top-Tier Journals to Achieve "One-Click" Conjugation
The global fields of immunotherapy and chemical biology have recently witnessed the publication of four major research findings—featured in Advanced Materials (IF > 27), the Journal of the American Chemical Society (JACS, a leading chemistry journal, with two papers), and ACS Nano (IF > 15). All four studies utilized the same innovative tool: the AND Linker, originally developed by Professor Xing Hang's team and commercialized by J&K Scientific. This technology enabled the researchers to achieve "one-click" conjugation of antibodies to DNA.
Evidence from Top-Tier Journals
Figure 1. Evidence from Top-Tier Journals (1): Hunan University, ACS Nano — Receptor-Tethered Cytosolic Modulators Demonstrate that "Location Determines Signaling Fate."Reference: Hu P, Wang Z, Wu L, et al. Receptor-Tethered Cytosolic Modulators Enable Spatial Control of Cell Signaling Specificity. ACS Nano. Published online June 22, 2026. doi:10.1021/acsnano.5c22746.
Figure 2. Evidence from Top-Tier Journals (2): South China University of Technology, Advanced Materials — Bispecific Antibody-Engineered MSCs for Precision Therapy of Inflammatory Bowel Disease.Reference: X. Liu, T. Ye, L. Yang, et al. “DNA-Scaffolded Bispecific Antibodies Enhance Mesenchymal Stromal Cell Therapy for Inflammatory Bowel Disease.” Adv. Mater.38, no. 4 (2026): e11854. https://doi.org/10.1002/adma.202511854.
IgG Antibody-DNA Conjugation Kit: The AND Linker, Upgraded!
At the core of this kit remains the AND Linker bifunctional fusion protein, originally developed by Professor Xing Hang's research team. This innovative technology enables:
1. Precision Targeting: Specifically binds to the Fc region of antibodies without interfering with antigen binding, preserving full antibody activity.
2. Quantitative Accuracy: Achieves precise 1:1 stoichiometric conjugation with uniform signal output, ensuring data reliability from the very source.
3. Cost-Effective & Convenient: Eliminates the need for ssDNA modifications; stable covalent bonding removes expensive base modification and purification steps, significantly reducing costs.
4. Rapid & Efficient: Completes the conjugation reaction in just 1 hour, streamlining your experimental workflow.
Why Trust Us?
1. Original Technology — Built on the core AND Linker technology from Professor Xing Hang's research group.
2. Validated by Top-Tier Journals — Endorsed by four publications at the Nature/Science sub-journal level.
3. Ready-to-Use — The kit contains all essential components: AND Linker lyophilized powder, proprietary reaction buffer, control ssDNA, and pure water. All components are pre-mixed and optimized, eliminating tedious trial-and-error and saving both time and effort.
4. Reliable Results — The included proprietary buffer system and control ssDNA ensure high experimental reproducibility, allowing for immediate validation of the conjugation system.
And Beyond: Unlimited Application Potential
From ultra-sensitive immunoassays (immuno-PCR) and proximity ligation assays (PLA) for protein interaction studies, to multi-omics integration and novel diagnostic probe development—the application landscape for the J&K Scientific IgG Antibody-DNA Conjugation Kit is rapidly expanding.
No tedious thiol reduction, no expensive modified nucleotides, no concerns about batch-to-batch variability.
With just 1 hour, 1-step reaction, and 1:1 precise conjugation, the J&K Scientific IgG Antibody-DNA Conjugation Kit ushers your antibody-DNA conjugation experiments into a new era of "one-click" precision.
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| Professor Xing Hang is affiliated with the Institute of Chemical Biology and Nanomedicine, the State Key Laboratory of Chemo/Biosensing and Chemometrics, and the College of Chemistry and Chemical Engineering at Hunan University. His research focuses on the interdisciplinary intersection of inorganic chemistry, nanomedicine, and chemical biology. He aims to develop novel chemical methods and material tools based on DNA, polymers, and inorganic crystalline materials, providing deeper insights into unknown biological processes and precision drug discovery. | 
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艳 李
