Azasaccharides are a class of sugar mimetics with important biological and pharmacological activities and play an important role in glycochemistry and glycobiology [1]. Studies have shown that azasugar exhibits excellent glycosidase inhibitory activity, glycosyltransferase inhibitory activity and nucleoside phosphorylase inhibitory activity. Therefore, azasugar has broad application prospects in the treatment of infections, cancer, obesity, metabolic disorders, and immunodeficiency diseases [2].
Azasugar drugs and enzyme inhibitors
J&K Scientific is by far the largest supplier of azasaccharides and their synthesis intermediates, with a total supply of more than 400 types to satisfy you:
One-stop direct shopping:
Provides a variety of aza sugars and their derivatives
Contains 5 sub-series such as polyhydroxypiperidine, polyhydroxypyrrolidine, and polyhydroxyindolizidine to meet diverse needs.
Design and synthesize by yourself:
Kilogram supply of polyhydroxy cyclic nitrones, an important intermediate for the synthesis of aza sugars;
Protective agents and solvents for sugar synthesis are available.
Yu Chuyi, Key Laboratory of Molecular Recognition and Function, Chinese Academy of Sciences, researcher, doctoral supervisor, 2012-01-01-present, National Monosaccharide Chemical Synthesis Engineering Technology Research Center, deputy director of the center, member of the technical committee, research direction: 1. Natural product chemistry 2, glycochemical biology
3. Heterocyclic chemistry
References
Li Yixian, Jia Yuemei, Yu Chuyi. Synthesis and Glycosidase Inhibitory Activity of Fluorinated Iminosugars. Progress in Chemistry, 2018, 30(5): 586-600.
Zhang Jichao. Synthesis of N-substituted Azacarb Glycosides and Their Derivatives[D]. University of Chinese Academy of Sciences, 2014.