Propofol EP Impurity O, 92.00%

Product Introduction

Propofol EP Impurity O (CAS No. 74663-48-2) is an alkyl-substituted phenol and is commonly identified as Propofol Impurity O. It has a phenolic hydroxyl group together with isopropyl and propyl substituents on the aromatic ring.

This compound is primarily used as a pharmaceutical impurity reference material for analytical research, impurity profiling, quality control, and method development associated with propofol-related materials.

Its well-defined chemical identity and molecular weight make it suitable for chromatographic and analytical applications where the identification and monitoring of propofol-related impurities are required.

Mechanism / Principle

Analytical Reference Material Function

Propofol EP Impurity O is primarily used as an analytical reference compound rather than as an active reagent in a specific biological mechanism.

In analytical applications:

• The compound provides a defined reference for impurity identification.
• Its chromatographic retention behavior can be compared with samples.
• It can be used to support impurity profiling and method validation.
• Its known molecular mass facilitates identification by mass spectrometry.

As Propofol Impurity O, it is particularly relevant to analytical testing of propofol-related substances.

Key Research Applications

1. Pharmaceutical Impurity Analysis

Propofol EP Impurity O is used as a reference material for pharmaceutical analytical research.

Applications include:

• Propofol impurity profiling
• Pharmaceutical quality control
• Impurity identification
• Related-substance analysis
• Analytical method development

2. HPLC and Chromatographic Analysis

The compound can be used as a reference standard when developing chromatographic methods for propofol-related substances.

Applications include:

• HPLC method development
• Related-substance testing
• Retention-time comparison
• Impurity quantification
• Chromatographic method validation

3. LC-MS and Mass Spectrometry

Its defined molecular composition makes it suitable for analytical identification using mass spectrometric techniques.

Applications include:

• LC-MS analysis
• Mass spectral identification
• Pharmaceutical impurity screening
• Structural confirmation
• Trace-level analytical research

4. Pharmaceutical Reference Standards

As a recognized propofol impurity, the compound can support pharmaceutical research and quality-control workflows.

Applications include:

• Reference standard development
• Stability studies
• Degradation-product investigation
• Batch quality assessment
• Regulatory analytical research

5. Analytical Chemistry Research

The compound can also serve as a model substituted phenol for analytical and chemical research.

Applications include:

• Phenolic compound analysis
• Analytical method development
• Structure-property studies
• Reference material research

Advantages

• Well-defined chemical identity
• Suitable propofol impurity reference material
• Useful for chromatographic analysis
• Compatible with LC-MS analytical workflows
• Supports pharmaceutical quality-control research
• Useful for impurity profiling and method development

Storage & Handling

• Store in a tightly closed container.
• Keep in a cool, dry, and well-ventilated area.
• Protect from moisture and contamination.
• Maintain the container upright and properly sealed after opening.
• Storage under an inert atmosphere at room temperature is specified for some research-grade products. 
• Follow the product-specific SDS for detailed handling and safety requirements.

Research Areas

Researchers working in the following fields may benefit from Propofol EP Impurity O (CAS No. 74663-48-2):

• Pharmaceutical analysis
• Pharmaceutical quality control
• Analytical chemistry
• Impurity profiling
• Chromatography
• LC-MS analysis
• Reference standard development
• Pharmaceutical research

Q1: What is Propofol EP Impurity O?

A: Propofol EP Impurity O is an alkyl-substituted phenol with the CAS number 74663-48-2. It is also known as Propofol Impurity O.

Q2: Is 74663-48-2 Propofol?

A: No. CAS 74663-48-2 is Propofol EP Impurity O, identified as Propofol Impurity O. It should not be confused with Propofol itself.

Q3: What is Propofol EP Impurity O used for?

A: It is mainly used as a reference material for propofol impurity analysis, pharmaceutical quality control, chromatographic method development, and analytical research.

Q4: What is the molecular formula?

A: The molecular formula is C₁₂H₁₈O, with a molecular weight of 178.27 g/mol.

Q5: What is Propofol Impurity O?

A: Propofol Impurity O is one of the names used for Propofol EP Impurity O (CAS 74663-48-2) in pharmaceutical impurity reference materials.

Q6: Can it be used for HPLC analysis?

A: Yes. It can be used as a reference compound for chromatographic method development and impurity profiling of propofol-related materials.

Q7: Can it be analyzed by LC-MS?

A: Yes. Its defined molecular formula and molecular weight make it suitable for LC-MS-based analytical identification.

Q8: How should Propofol EP Impurity O be stored?

A: Keep the container tightly closed in a dry, well-ventilated environment. Some research-grade suppliers specify room-temperature storage under an inert atmosphere.