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Macitentan Impurity 7

Cat. No S57C4X-11757_10_MG
US-CATO

Product Information

Product Name
Macitentan Impurity 7
Brand Name
US-CATO
Product Number
C4X-11757
CAS
1433875-21-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
67041378
IUPAC Name
5-(4-bromophenyl)-6-2-(5-bromopyrimidin-2-yl)oxyethoxypyrimidin-4-amine
InChI Key
LFEPQTGGEXKQEY-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)N)Br

References

Improved and single-pot process for the synthesis of macitentan, an endothelin receptor antagonist, via lithium amide-mediated nucleophilic substitution
Publication Name: Monatshefte für Chemie - Chemical Monthly
Publication Date: 2018-01-16
DOI: 10.1007/s00706-017-2098-2

Separation and Characterization of New Forced Degradation Products of Macitentan: A Dual Endothelin Receptor Antagonist
Publication Name: Chromatographia
Publication Date: 2018-01-16
DOI: 10.1007/s10337-018-3471-y

Macitentan Impurity 7

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