(S)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl (S)-(-)-H8-BINAP

Technical Notes:
1.Biaryl bisphosphine ligand.The H8-BINAP ligand,as the ruthenium complex, catalyzes hydrogenation of unsaturated carboxylic acids to a higher ee than does BINAP.(Ref.1.2)
2.The ruthenium catalyzed hydrogenation of aryl propenoic acid to produce the drug lbuprofen.
3.Rhodium catalyzed asymmetric regioselective 1.4-addition of arylboronic acids to 3-substituted maleimides
4.Ligand for palladium-catalyzed enantioselective hydrogenation of substituted indoles.
5.Rhodium-catalyzed enantioselective cyclization of Y-alkynylaldehydes with acyl phosphonates.
6.Enantioselective synthesis of axially chiral 1-arylisoquinolines by Rh-catalyzed [2+2+2][2+2+2] cycloaddition of a,w-diynes with arylisocyanates
10.Asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)-indoles
11.Asymmetric Rh(1-catalyzed intramolecular [3+2] cycloaddition of 1-yne-vinylcyclopropanes for bicyclo[3.3.0] compounds with
a chiral quaternary carbon stereocenter.
12. Enantioselective intermolecular[2+2+2][2+2+2] trimerization/asymmetric intramolecular [4+2] cycloaddition of two aryl ethynyl
ethers and 5-alkynals.
14.Rh-catalyzed regio-, diastereo-, and enantioselective [2+2+2] cycloaddition of 1.6-enynes with acrylamides.