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Sku CI05747_1_G
Chem Impex
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Product Information

Product Name
Fmoc-L-norleucine N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
05747
CAS
201026-08-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
56777016
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoate
InChI Key
VXZUSHCSKUMSHO-NRFANRHFSA-N
SMILES
CCCCC@@H(C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Description

Fmoc-L-norleucine N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures efficiently. Its protective Fmoc group enables selective deprotection, facilitating the stepwise assembly of peptides.

Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs, particularly in targeting specific biological pathways. Its stability and reactivity make it an excellent candidate for creating therapeutic agents.

Bioconjugation: The N-hydroxysuccinimide (NHS) moiety allows for efficient coupling to amine-containing molecules, making it valuable in creating bioconjugates for diagnostics and targeted drug delivery systems.

Protein Engineering: This compound is utilized in modifying proteins to enhance their properties, such as stability and solubility, which is crucial in developing effective biopharmaceuticals.

Research in Cancer Therapeutics: Its application in creating targeted therapies for cancer treatment highlights its importance in developing innovative solutions to combat complex diseases.