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Sku CI16199_1_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-6-hydroxynorleucine
Brand Name
Chem Impex
Product Number
16199
CAS
374899-60-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
51340510
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-hydroxyhexanoic acid
InChI Key
RLKMUBZYLZBKMO-IBGZPJMESA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CCCCO)C(=O)O

Application

Na-Fmoc-6-hydroxynorleucine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptide structures.

Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific biological pathways, enhancing the efficacy of therapeutic agents.

Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to other molecules, facilitating the development of targeted drug delivery systems.

Research in Protein Engineering: Researchers utilize it in studies aimed at modifying proteins to improve their stability and activity, which is crucial for developing better biopharmaceuticals.

Analytical Chemistry: It is employed in analytical methods to study protein interactions and dynamics, providing insights that are vital for understanding biological processes.

References

LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells

Publication Name: Oncogene
Publication Date: 2019-08-28
DOI: 10.1038/s41388-019-0969-1