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Sku CI03993_100_G
Chem Impex
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Product Information

Product Name
Boc-L-leucine 4-nitrophenyl ester
Brand Name
Chem Impex
Product Number
03993
CAS
3350-19-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
1810201
IUPAC Name
(4-nitrophenyl) (2S)-4-methyl-2-(2-methylpropan-2-yl)oxycarbonylaminopentanoate
InChI Key
HCKZUUZDQIKPEF-AWEZNQCLSA-N
SMILES
CC(C)CC@@H(C(=O)OC1=CC=C(C=C1)N+(=O)O-)NC(=O)OC(C)(C)C

Description

Boc-L-leucine 4-nitrophenyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enhancing the efficiency of coupling reactions.

Drug Development: It is used in the design of prodrugs, which can improve the bioavailability of therapeutic agents by modifying their solubility and absorption characteristics.

Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted drug delivery systems.

Research in Enzyme Inhibition: It acts as a substrate or inhibitor in enzyme studies, helping researchers understand enzyme mechanisms and develop new inhibitors.

Analytical Chemistry: Boc-L-leucine 4-nitrophenyl ester is employed in chromatography and mass spectrometry, aiding in the separation and identification of complex mixtures.

References Data Source From Pubchem

A Simple Synthesis of Imide-Dipeptides

Publication Name: Synlett
Publication Date: 2009-05-13
DOI: 10.1055/s-0029-1217167

Swellographic Study of Peptide Resin Swelling Behavior during Solid Phase Peptide Synthesis

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2007-02-22
DOI: 10.1007/s10989-006-9061-0

The N‐end rule pathway controls the import of peptides through degradation of a transcriptional repressor

Publication Name: The EMBO Journal
Publication Date: 1998-01-01
DOI: 10.1093/emboj/17.1.269

Synthesis and investigation of the antitumoral activity of shortened analogs of luliberin

Publication Name: Chemistry of Natural Compounds
Publication Date: 1994-09-01
DOI: 10.1007/bf00629874

Synthesis and study of the biological activity of fragments of salmon calcitonin II

Publication Name: Chemistry of Natural Compounds
Publication Date: 1993-01
DOI: 10.1007/bf00631034