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Sku CI02440_1_G
Chem Impex
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Product Information

Product Name
Fmoc-L-norleucine
Brand Name
Chem Impex
Product Number
02440
CAS
77284-32-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7009636
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
InChI Key
VCFCFPNRQDANPN-IBGZPJMESA-N
SMILES
CCCCC@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-L-norleucine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.

Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs, offering potential therapeutic benefits due to its structural properties that enhance bioactivity.

Bioconjugation: Fmoc-L-norleucine is employed in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in the development of targeted drug delivery systems.

Protein Engineering: Researchers utilize this compound in protein engineering to modify proteins for improved stability and functionality, which is essential in various biotechnological applications.

Research in Neuroscience: It is also used in studies related to neuropeptides, contributing to the understanding of neurotransmitter functions and potential treatments for neurological disorders.

References

Apoptosis-inducing photodynamic therapy via dual-wavelength responsive ICG/Ce6 incorporated mesoporous silica nanoparticles in prostate cancer cells

Publication Name: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Publication Date: 2025-07-26
DOI: 10.1007/s43630-025-00759-y

Synthesis of ZIF-8 Coated MnO2 Functionalized Antibacterial Peptide Nanoparticles and Its Antibacterial and Wound-Healing Promotion Studies

Publication Name: Current Microbiology
Publication Date: 2025-07-26
DOI: 10.1007/s00284-025-04378-9

Syringaldehyde Ameliorates Cognitive Dysfunction in APP/PS1 Mice by Stabilizing the NLRP3 Pathway

Publication Name: Molecular Neurobiology
Publication Date: 2025-07-25
DOI: 10.1007/s12035-025-05227-3

Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies

Publication Name: Leukemia
Publication Date: 2025-07-24
DOI: 10.1038/s41375-025-02694-4