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Chem Impex
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Product Information

Product Name
Fmoc-S-acetamidomethyl-L-cysteine
Brand Name
Chem Impex
Product Number
02396
CAS
86060-81-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
128799
IUPAC Name
(2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChI Key
CSMYOORPUGPKAP-IBGZPJMESA-N
SMILES
CC(=O)NCSCC@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-S-acetamidomethyl-L-cysteine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), enabling researchers to create complex peptide structures efficiently.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific proteins or enzymes.

Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.

Research in Protein Engineering: It plays a significant role in protein engineering, where modifications can enhance protein stability and activity, leading to better therapeutic outcomes.

Analytical Chemistry: Fmoc-S-acetamidomethyl-L-cysteine is employed in analytical techniques to study protein interactions and modifications, providing insights into biological processes.

References

Ruthenium-Catalyzed One-pot Peptide Ligation

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4486-7_2

Mirror-image trypsin digestion and sequencing of D-proteins

Publication Name: Nature Chemistry
Publication Date: 2024-01-18
DOI: 10.1038/s41557-023-01411-x

Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation

Publication Name: Nature Chemical Biology
Publication Date: 2022-06-08
DOI: 10.1038/s41589-022-01059-7

Hydrogel Formation with Enzyme-ResponsiveEnzyme-responsive Cyclic Peptides

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2022
DOI: 10.1007/978-1-0716-1689-5_23

Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor

Publication Name: Marine Life Science & Technology
Publication Date: 2021-07-22
DOI: 10.1007/s42995-021-00108-9