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Product Information

Product Name
Acetyl-L-cysteine
Brand Name
Chem Impex
Product Number
00839
CAS
616-91-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12035
IUPAC Name
(2R)-2-acetamido-3-sulfanylpropanoic acid
InChI Key
PWKSKIMOESPYIA-BYPYZUCNSA-N
SMILES
CC(=O)NC@@H(CS)C(=O)O

Application

Acetyl-L-cysteine is widely utilized in research focused on:

Respiratory Health: Commonly used as a mucolytic agent, it helps break down mucus in conditions like chronic obstructive pulmonary disease (COPD) and cystic fibrosis, improving lung function and patient comfort.

Antioxidant Therapy: Acts as a precursor to glutathione, a powerful antioxidant, it supports cellular health and is used in various therapeutic strategies to combat oxidative stress in diseases such as Alzheimer's and Parkinson's.

Pharmaceutical Formulations: Frequently included in formulations for its ability to enhance drug solubility and stability, making it valuable in the development of various medications.

Detoxification: Utilized in emergency medicine as an antidote for acetaminophen overdose, it helps to replenish glutathione levels, preventing liver damage and promoting recovery.

Cosmetic Applications: Incorporated in skincare products for its skin-rejuvenating properties, it helps improve skin texture and reduce signs of aging, appealing to the beauty industry.

References

Enantiospecific hepatotoxicity of usnic acid in vitro, and the attempt to modify the toxic effect

Publication Name: Toxicology
Publication Date: 2025-09
DOI: 10.1016/j.tox.2025.154189

N-acetyl-L-cysteine promoted hematopoietic recovery in patients with acute myeloid leukemia after complete remission--A pilot study

Publication Name: Cancer Letters
Publication Date: 2025-08-10
DOI: 10.1016/j.canlet.2025.217812

FKBP51 protects hair cells of utricles from gentamicin-induced toxicity in vitro: possible relation to the activities of NF-κB signaling pathway

Publication Name: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Publication Date: 2025-08
DOI: 10.1016/j.fct.2025.115513

Evaluating N-acetylcysteine for mitigating cisplatin-induced oxidative stress and ionocyte damage in a zebrafish model

Publication Name: Toxicology and Applied Pharmacology
Publication Date: 2025-08
DOI: 10.1016/j.taap.2025.117401

Design, synthesis, and biological evaluation of ACF-03: a novel anti-fibrotic and antioxidant agent targeting ROS-TGF-β1-HIF-1α axis

Publication Name: Applied Biological Chemistry
Publication Date: 2025-07-30
DOI: 10.1186/s13765-025-01007-8