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Sku CI00774_250_G
Chem Impex
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Product Information

Product Name
Boc-L-leucine hydrate
Brand Name
Chem Impex
Product Number
00774
CAS
200936-87-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
12373896
IUPAC Name
(2S)-4-methyl-2-(2-methylpropan-2-yl)oxycarbonylaminopentanoic acid;hydrate
InChI Key
URQQEIOTRWJXBA-QRPNPIFTSA-N
SMILES
CC(C)CC@@H(C(=O)O)NC(=O)OC(C)(C)C.O

Description

Boc-L-leucine hydrate is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptide structures in pharmaceuticals.

Drug Development: Its role in drug formulation is significant, particularly in designing prodrugs that enhance bioavailability. Researchers leverage its properties to improve the efficacy of therapeutic agents.

Biotechnology: In the production of recombinant proteins, Boc-L-leucine hydrate is used to facilitate the incorporation of leucine into proteins, which can enhance their stability and functionality in various applications.

Research in Molecular Biology: It is utilized in studies involving protein interactions and enzyme activity, providing insights into cellular mechanisms and aiding in the development of targeted therapies.

Cosmetic Formulations: The compound finds application in the cosmetic industry, where it is used in formulations aimed at improving skin hydration and texture, leveraging its biochemical properties for skin health.

References Data Source From Pubchem

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor

Publication Name: Nature Chemical Biology
Publication Date: 2008-12-07
DOI: 10.1038/nchembio.132

Synthesis of the amide of the C-terminal tetrapeptide of the sequence of oxytocin

Publication Name: Chemistry of Natural Compounds
Publication Date: 1992-05
DOI: 10.1007/bf00630256