Product Name
Gentamicin sulfate
Certificate of Analysis (COA)
IUPAC Name
(2R,3R,4R,5R)-2-(1S,2S,3R,4S,6R)-4,6-diamino-3-(2R,3R,6S)-3-amino-6-(1-aminoethyl)oxan-2-yloxy-2-hydroxycyclohexyloxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2R,3R,4R,5R)-2-(1S,2S,3R,4S,6R)-4,6-diamino-3-(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yloxy-2-hydroxycyclohexyloxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2R,3R,4R,5R)-2-(1S,2S,3R,4S,6R)-4,6-diamino-3-(2R,3R,6S)-3-amino-6-1-(methylamino)ethyloxan-2-yloxy-2-hydroxycyclohexyloxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
InChI Key
RDEIXVOBVLKYNT-VQBXQJRRSA-N
SMILES
CC(C@@H1CCC@H(C@H(O1)OC@@H2C@H(CC@H(C@@H(C@H2O)OC@@H3C@@H(C@H(C@@(CO3)(C)O)NC)O)N)N)N)N.CC(C@@H1CCC@H(C@H(O1)OC@@H2C@H(CC@H(C@@H(C@H2O)OC@@H3C@@H(C@H(C@@(CO3)(C)O)NC)O)N)N)N)NC.CC@@1(COC@@H(C@@H(C@H1NC)O)OC@H2C@@H(CC@@H(C@H(C@@H2O)OC@@H3C@@H(CCC@H(O3)CN)N)N)N)O.OS(=O)(=O)O
Gentamicin sulfate is widely utilized in research focused on:
Antibiotic Treatments: It is primarily used to treat serious bacterial infections, especially those caused by Gram-negative bacteria, making it essential in hospitals and clinics.
Veterinary Medicine: This compound is commonly used in veterinary practices to treat infections in animals, ensuring their health and well-being.
Pharmaceutical Formulations: Gentamicin sulfate is a key ingredient in various topical and injectable formulations, providing effective treatment options for patients.
Research Applications: In laboratory settings, it is used to study bacterial resistance mechanisms, helping researchers develop new antibiotics.
Quality Control in Manufacturing: The compound is utilized in the pharmaceutical industry for quality control testing to ensure the efficacy and safety of antibiotic products.
National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.