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2'-Deoxy-2'-fluoroadenosine, 98%|927893|64183-27-3

2'-Deoxy-2'-fluoroadenosine, 98%

Cat. No JK927893_250_MG
J&K Chemical

Product Information

Product Name
2'-Deoxy-2'-fluoroadenosine, 98%
Brand Name
J&K
Product Number
927893
CAS
64183-27-3
Molecular Formula
C10H12FN5O3
Molecular Weight
269.24
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
  • 9-(2-Fluoro-2-deoxy-b-D-ribofuranosyI)-adenine
  • 2'-Fluoro-2'-deoxy-D-adenosine
PubChem CID
100253
IUPAC Name
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
InChI Key
ZGYYPTJWJBEXBC-QYYRPYCUSA-N
SMILES
C1=NC(=C2C(=N1)N(C=N2)C@H3C@@H(C@@H(C@H(O3)CO)O)F)N

Safety Information

GHS Symbols
Hazard Symbol
Signal Word
Warning
Hazard Statement
H302
H312
H332
H315
H319
H335
Precautionary Statement
P270
P330
P501
P280
P321
P261
P271
P319
P405
P301+P317
P302+P352
P362+P364
P304+P340
P332+P317
P264+P265
P305+P351+P338
P337+P317
P403+P233

References Data Source From Pubchem

Sugar-modified nucleosides from simple ingredients
Publication Name: Nature Synthesis
Publication Date: 2024-11-05
DOI: 10.1038/s44160-024-00645-y

Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases
Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2015-06-15
DOI: 10.1016/j.bmcl.2015.04.073

Evaluation of 2′-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase
Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2013-06-01
DOI: 10.1016/j.bmcl.2013.03.095

S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: Potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,d-arabinofuranosyl)adenine
Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2012-06-15
DOI: 10.1016/j.bmcl.2012.03.087

Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY
Publication Name: Nature Chemical Biology
Publication Date: 2007-11-18
DOI: 10.1038/nchembio.2007.40

2'-Deoxy-2'-fluoroadenosine, 98%

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