(D-Arg1,D-Phe5,D-Trp7·9,Leu11)-Substance P

Name: (D-Arg1,D-Phe5,D-Trp7·9,Leu11)-Substance P | 96736-12-8
Brand: US-CATO
SKU: S57CPTD787532_10_MG
Price: 19998.0 USD
Availability: OutOfStock

Cat. No S57CPTD787532_10_MG

Vendor: US-CATO

Product Information

Product Name

(D-Arg1,D-Phe5,D-Trp7·9,Leu11)-Substance P

Brand Name

US-CATO

Product Number

CPTD787532

CAS

96736-12-8

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

25077998

IUPAC Name

(2S)-2-(2S)-2-(2S)-1-(2S)-6-amino-2-(2S)-1-(2S)-2-amino-5-(diaminomethylideneamino)pentanoylpyrrolidine-2-carbonylaminohexanoylpyrrolidine-2-carbonylamino-3-phenylpropanoylamino-N-(2S)-1-(2S)-1-(2S)-1-(2S)-1-(2S)-1-amino-4-methyl-1-oxopentan-2-ylamino-4-methyl-1-oxopentan-2-ylamino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino-1-oxo-3-phenylpropan-2-ylamino-3-(1H-indol-3-yl)-1-oxopropan-2-ylpentanediamide

InChI Key

XVOCEQLNJQGCQG-UNAVROQCSA-N

SMILES

CC(C)CC@@H(C(=O)N)NC(=O)C@H(CC(C)C)NC(=O)C@H(CC1=CNC2=CC=CC=C21)NC(=O)C@H(CC3=CC=CC=C3)NC(=O)C@H(CC4=CNC5=CC=CC=C54)NC(=O)C@H(CCC(=O)N)NC(=O)C@H(CC6=CC=CC=C6)NC(=O)C@@H7CCCN7C(=O)C@H(CCCCN)NC(=O)C@@H8CCCN8C(=O)C@H(CCCN=C(N)N)N

References Data Source From Pubchem

2-Aminoalkyl nicotinamide derivatives as pure inverse agonists of the ghrelin receptor

Publication Name: Bioorganic & Medicinal Chemistry Letters

Publication Date: 2015-07-01

DOI: 10.1016/j.bmcl.2015.04.040

The antiproliferative action of [D-Arg(1), D-Phe(5), D-Trp(7,9), LEU(11)] substance P analogue antagonist against small-cell- and non-small-cell lung cancer cells could be due to the pharmacological profile of its tachykinin receptor antagonist

Publication Name: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

Publication Date: 2015-06

Emoghrelin, a unique emodin derivative in Heshouwu, stimulates growth hormone secretion via activation of the ghrelin receptor

Publication Name: Journal of Ethnopharmacology

Publication Date: 2015-01-15

DOI: 10.1016/j.jep.2014.10.063

Abnormal Response to the Anorexic Effect of GHS-R Inhibitors and Exenatide in Male Snord116 Deletion Mouse Model for Prader-Willi Syndrome

Publication Name: Endocrinology

Publication Date: 2014-07-01

DOI: 10.1210/en.2013-2083

Intrarenal Ghrelin Receptor Antagonism Prevents High-Fat Diet-Induced Hypertension in Male Rats

Publication Name: Endocrinology

Publication Date: 2014-07-01

DOI: 10.1210/en.2013-2177

(D-Arg1,D-Phe5,D-Trp7·9,Leu11)-Substance P

Product Information

General Information

References Data Source From Pubchem

2-Aminoalkyl nicotinamide derivatives as pure inverse agonists of the ghrelin receptor

The antiproliferative action of [D-Arg(1), D-Phe(5), D-Trp(7,9), LEU(11)] substance P analogue antagonist against small-cell- and non-small-cell lung cancer cells could be due to the pharmacological profile of its tachykinin receptor antagonist

Emoghrelin, a unique emodin derivative in Heshouwu, stimulates growth hormone secretion via activation of the ghrelin receptor

Abnormal Response to the Anorexic Effect of GHS-R Inhibitors and Exenatide in Male Snord116 Deletion Mouse Model for Prader-Willi Syndrome

Intrarenal Ghrelin Receptor Antagonism Prevents High-Fat Diet-Induced Hypertension in Male Rats