Dynorphin A (1-13) amide|CPTD787488|79515-34-7

Dynorphin A (1-13) amide

Cat. No S57CPTD787488_10_MG

Vendor: US-CATO

Product Information

Product Name

Dynorphin A (1-13) amide

Brand Name

US-CATO

Product Number

CPTD787488

CAS

79515-34-7

Certificate of Analysis (COA)

COA not found

General Information

PubChem CID

25079852

IUPAC Name

(2S)-N-(2S)-6-amino-1-(2S)-1-(2S)-1,6-diamino-1-oxohexan-2-ylamino-4-methyl-1-oxopentan-2-ylamino-1-oxohexan-2-yl-1-(2S)-2-(2S,3S)-2-(2S)-2-(2S)-2-(2S)-2-(2S)-2-2-2-(2S)-2-amino-3-(4-hydroxyphenyl)propanoylaminoacetylaminoacetylamino-3-phenylpropanoylamino-4-methylpentanoylamino-5-(diaminomethylideneamino)pentanoylamino-5-(diaminomethylideneamino)pentanoylamino-3-methylpentanoylamino-5-(diaminomethylideneamino)pentanoylpyrrolidine-2-carboxamide

InChI Key

YJLKYUMEUZAMMP-IWIISZHXSA-N

SMILES

CCC@H(C)C@@H(C(=O)NC@@H(CCCN=C(N)N)C(=O)N1CCCC@H1C(=O)NC@@H(CCCCN)C(=O)NC@@H(CC(C)C)C(=O)NC@@H(CCCCN)C(=O)N)NC(=O)C@H(CCCN=C(N)N)NC(=O)C@H(CCCN=C(N)N)NC(=O)C@H(CC(C)C)NC(=O)C@H(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C@H(CC3=CC=C(C=C3)O)N

References Data Source From Pubchem

Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2023-08-26

DOI: 10.1021/acs.jmedchem.3c00426

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2021-06-24

DOI: 10.1021/acs.jmedchem.1c00158

Conopeptide-Derived κ-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2016-02-22

DOI: 10.1021/acs.jmedchem.5b00911

Synthesis and Opioid Activity of Side-Chain-to-Side-Chain Cyclic Dynorphin A-(1−11) Amide Analogues Cyclized between Positions 2 and 5. 1. Substitutions in Position 3

Publication Name: Journal of Medicinal Chemistry

Publication Date: 2003-12-17

DOI: 10.1021/jm030298e

Additions and Corrections - Synthesis and Opioid Activity of Dynorphin-A-(1-13)NH2 Analogues Containing cis- and trans-4-Aminocyclohexanecarboxylic Acid

Publication Name: Journal of Medicinal Chemistry

Publication Date: 1993-06-25

DOI: 10.1021/jm00060a018|10.1021/jm00065a602