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Sku CI12770_1_G
Chem Impex
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Product Information

Product Name
Fmoc-L-b-homoleucine
Brand Name
Chem Impex
Product Number
12770
CAS
193887-44-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2761527
IUPAC Name
(3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methylhexanoic acid
InChI Key
YLVSABQQLLRFIJ-HNNXBMFYSA-N
SMILES
CC(C)CC@@H(CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Description

Fmoc-L-b-homoleucine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.

Drug Development: Its unique properties make it valuable in pharmaceutical research, where it can be incorporated into drug candidates, enhancing their stability and bioavailability.

Bioconjugation: Fmoc-L-b-homoleucine is used in bioconjugation processes, linking biomolecules like proteins and antibodies to therapeutic agents, which is essential in targeted drug delivery systems.

Research in Protein Engineering: This compound aids in the design of modified proteins, enabling researchers to explore new functionalities and improve existing protein-based therapies.

Analytical Chemistry: It is utilized in the development of analytical methods for the characterization of peptides and proteins, providing insights into their structure and function.

References Data Source From Pubchem

A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β- and γ-amino acids

Publication Name: Amino Acids
Publication Date: 2011-06-03
DOI: 10.1007/s00726-011-0941-z

Metal-Catalyzed Wolff Rearrangement

Publication Name: Science of Synthesis
Publication Date: 2006