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Sku CI07038_100_MG
Chem Impex
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Product Information

Product Name
6-Diazo-5-oxo-L-norleucine
Brand Name
Chem Impex
Product Number
07038
CAS
157-03-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
9087
IUPAC Name
(2S)-2-amino-6-diazo-5-oxohexanoic acid
InChI Key
YCWQAMGASJSUIP-YFKPBYRVSA-N
SMILES
C(CC(=O)C=N+=N-)C@@H(C(=O)O)N

Description

6-Diazo-5-oxo-L-norleucine is widely utilized in research focused on:

Enzyme Inhibition Studies: This compound serves as a potent inhibitor of various enzymes, particularly in studies related to amino acid metabolism, allowing researchers to explore metabolic pathways and enzyme functions.

Neuropharmacology: It is used in neuropharmacological research to investigate its effects on neurotransmitter systems, which can lead to potential therapeutic applications in treating neurological disorders.

Biochemical Research: The compound is valuable in biochemical assays to study the effects of amino acid analogs on protein synthesis, helping scientists understand protein interactions and functions.

Drug Development: 6-Diazo-5-oxo-L-norleucine is explored in the development of new pharmaceuticals, particularly those targeting metabolic diseases, due to its unique structural properties that influence biological activity.

Plant Biology: Researchers utilize this compound to study plant growth and development, particularly in understanding how amino acid analogs affect plant metabolism and stress responses.

References Data Source From Pubchem

Nitric Oxide Synthase Dysregulation in Hyperammonemia: Opportunities and Challenges Toward Therapeutic Targeting to Combat Neurological Complications

Publication Name: Neurochemical Research
Publication Date: 2026-02-28
DOI: 10.1007/s11064-026-04706-w

Hyperglutaminolysis drives senescence and aging through arginine-mTORC1 axis activation

Publication Name: Signal Transduction and Targeted Therapy
Publication Date: 2026-02-19
DOI: 10.1038/s41392-026-02576-w

Regulation of grain protein content by the amino acid permease gene OsAAP4 in rice

Publication Name: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Publication Date: 2026-01-28
DOI: 10.1007/s00122-026-05158-0

Inhibition of glutamine metabolism blocks tumor growth and sensitizes ccRCC to immune checkpoint blockade

Publication Name: Journal of Translational Medicine
Publication Date: 2026-01-24
DOI: 10.1186/s12967-026-07705-1

Glutamine: fructose-6-phosphate amidotransferase (GFAT) in the pathology of diseases: a review

Publication Name: Cell Death Discovery
Publication Date: 2025-12-14
DOI: 10.1038/s41420-025-02898-8