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Sku CI03672_5_G
Chem Impex
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Product Information

Product Name
Boc-L-leucine N-hydoxysuccinimide ester
Brand Name
Chem Impex
Product Number
03672
CAS
3392-09-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11023929
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S)-4-methyl-2-(2-methylpropan-2-yl)oxycarbonylaminopentanoate
InChI Key
WXRGJQZMGGGTSS-JTQLQIEISA-N
SMILES
CC(C)CC@@H(C(=O)ON1C(=O)CCC1=O)NC(=O)OC(C)(C)C

Description

Boc-L-leucine N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing for the introduction of leucine residues, which are crucial for protein structure and function.

Drug Development: It is used in the design of prodrugs that enhance the solubility and bioavailability of therapeutic agents, improving their effectiveness in clinical applications.

Bioconjugation: The ester functionality enables efficient conjugation with biomolecules, facilitating the development of targeted drug delivery systems and diagnostic agents.

Research in Biochemistry: Researchers utilize this compound to study protein interactions and modifications, providing insights into various biological processes and disease mechanisms.

Custom Synthesis Services: It is often employed by chemical manufacturers and laboratories for custom synthesis projects, catering to specific research needs and applications in various industries.

References Data Source From Pubchem

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Synthesis and Structure—Activity (Anxiolytic) Relationship Analysis of Leucyltryptophan Ligands of 18-KDA Translocator Protein

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2020-09-29
DOI: 10.1007/s11094-020-02241-8

High specific activity tritium labelling of biologically active small peptides and a related analogue

Publication Name: Journal of Radioanalytical and Nuclear Chemistry
Publication Date: 2015-05-08
DOI: 10.1007/s10967-015-4158-6

Monitoring subcellular biotransformation of N-l-leucyldoxorubicin by micellar electrokinetic capillary chromatography coupled to laser-induced fluorescence detection

Publication Name: Analytical and Bioanalytical Chemistry
Publication Date: 2014-02-27
DOI: 10.1007/s00216-014-7615-0

Primed-site Probing of Papain-like Cysteine Proteases

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2006-12-02
DOI: 10.1007/s10989-006-9050-3