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Acetyl-L-leucine amide|02619|28529-34-2

Acetyl-L-leucine amide

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Sku CI02619_1_G
Chem Impex
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Product Information

Product Name
Acetyl-L-leucine amide
Brand Name
Chem Impex
Product Number
02619
CAS
28529-34-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
140111
IUPAC Name
(2S)-2-acetamido-4-methylpentanamide
InChI Key
PHPXQAHAQREGGN-ZETCQYMHSA-N
SMILES
CC(C)CC@@H(C(=O)N)NC(=O)C

Description

Acetyl-L-leucine amide is widely utilized in research focused on:

Neuroprotective Research: This compound is studied for its potential benefits in neurodegenerative diseases, offering insights into protective mechanisms against neuronal damage.

Metabolic Disorders: It plays a role in understanding metabolic pathways, particularly in conditions like obesity and diabetes, helping researchers explore therapeutic options.

Pharmaceutical Development: The compound is investigated for its ability to enhance drug solubility and bioavailability, making it valuable in the formulation of new medications.

Sports Nutrition: It is explored for its potential to improve muscle recovery and performance, appealing to athletes and fitness enthusiasts looking for effective supplements.

Cosmetic Applications: Acetyl-L-leucine amide is being evaluated for its skin benefits, particularly in anti-aging formulations, providing a natural option for skincare products.

References Data Source From Pubchem

Solubilities and Transfer Free Energies of Hydrophobic Amino Acids in Polyol Solutions: Importance of the Hydrophobicity of Polyols
Publication Name: Journal of Pharmaceutical Sciences
Publication Date: 2011-08
DOI: 10.1002/jps.22584

Solvation Dynamics of Model Peptides Probed by Terahertz Spectroscopy. Observation of the Onset of Collective Network Motions
Publication Name: Journal of the American Chemical Society
Publication Date: 2009-02-25
DOI: 10.1021/ja808997y

Hydration Dynamics of Water near an Amphiphilic Model Peptide at Low Hydration Levels: A Dielectric Relaxation Study
Publication Name: Chemphyschem : a European journal of chemical physics and physical chemistry
Publication Date: 2008-12-15
DOI: 10.1002/cphc.200800508

Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and analysis of their interactions with lectins
Publication Name: Carbohydrate Research
Publication Date: 2007-07-02
DOI: 10.1016/j.carres.2007.03.010

Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells
Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2003-02-07
DOI: 10.1016/s0006-291x(02)03052-8