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Sku CI46909_25_G
Chem Impex
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Product Information

Product Name
N2-Isobutyryl-2'-O-methylguanosine
Brand Name
Chem Impex
Product Number
46909
CAS
63264-29-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135536008
IUPAC Name
N-9-(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl-6-oxo-1H-purin-2-yl-2-methylpropanamide
InChI Key
RPULCYXEYODQOG-AKAIJSEGSA-N
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C@H3C@@H(C@@H(C@H(O3)CO)O)OC

Application

N2-Isobutyryl-2'-O-methylguanosine is widely utilized in research focused on:

Nucleotide Synthesis: This compound serves as a key building block in the synthesis of modified nucleotides, which are essential for developing new RNA-based therapeutics and diagnostics.

Drug Development: It plays a significant role in pharmaceutical research, particularly in designing antiviral drugs that target RNA viruses, enhancing the efficacy of treatments.

Biochemical Studies: Researchers use it to study RNA interactions and modifications, providing insights into cellular processes and potential disease mechanisms.

Gene Expression Analysis: The compound is employed in assays to analyze gene expression, helping scientists understand how genes are regulated in various conditions.

Therapeutic Applications: Its unique structure allows for the development of novel therapeutic agents that can improve the delivery and stability of RNA molecules in therapeutic contexts.

References Data Source From Pubchem

Synthesis and biochemical application of 2′-O-methyl-3′-thioguanosine as a probe to explore group I intron catalysis

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2008-05-15
DOI: 10.1016/j.bmc.2008.03.061