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Sku CI42106_5_MG
Chem Impex
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Product Information

Product Name
Guanosine 5?-diphospho-b-L-fucose sodium salt
Brand Name
Chem Impex
Product Number
42106
CAS
15839-70-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135412609
IUPAC Name
(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-ylmethoxy-hydroxyphosphoryl (3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl hydrogen phosphate
InChI Key
LQEBEXMHBLQMDB-QIXZNPMTSA-N
SMILES
CC@H1C@H(C@H(C@@H(C(O1)OP(=O)(O)OP(=O)(O)OCC@@H2C@H(C@H(C@@H(O2)N3C=NC4=C3N=C(NC4=O)N)O)O)O)O)O

Application

Guanosine 5'-diphospho-b-L-fucose sodium salt is widely utilized in research focused on:

Cell Signaling Studies: This compound plays a crucial role in cell signaling pathways, making it essential for researchers studying cellular communication and responses.

Glycobiology: It is significant in the field of glycobiology, aiding in the understanding of glycoproteins and their functions, which is vital for drug development and therapeutic applications.

Biotechnology: Used in the production of recombinant proteins, it enhances the efficiency of protein expression systems, benefiting industries like pharmaceuticals and biotechnology.

Immunology Research: Its application in immunology helps in studying immune responses, which is critical for vaccine development and understanding autoimmune diseases.

Diagnostics: This compound is utilized in diagnostic assays, providing insights into various diseases by serving as a biomarker for specific conditions.

References Data Source From Pubchem

GDP ‐fucose transporter SLC35C1 : a potential regulatory role in cytosolic GDP ‐fucose and fucosylated glycan synthesis

Publication Name: FEBS Open Bio
Publication Date: 2025-05-27
DOI: 10.1002/2211-5463.70057

Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase

Publication Name: The Journal of biological chemistry
Publication Date: 2025-04
DOI: 10.1016/j.jbc.2025.108344

Use of Crithidia fasciculata extract for the facile enzymatic synthesis of GDP-L-[3H]Fucose

Publication Name: Glycobiology
Publication Date: 2024-12-21
DOI: 10.1093/glycob/cwae097

Interplay between de novo and salvage pathways of GDP-fucose synthesis

Publication Name: PLOS ONE
Publication Date: 2024-10-24
DOI: 10.1371/journal.pone.0309450

Engineering Escherichia coli for Highly Efficient Biosynthesis of Lacto-N-difucohexaose II through De Novo GDP-l-fucose Pathway

Publication Name: Journal of Agricultural and Food Chemistry
Publication Date: 2024-04-25
DOI: 10.1021/acs.jafc.4c01264