$221.70

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku CI00873_250_MG
Chem Impex
Get Bulk Quote

Product Information

Product Name
2',3'-Dideoxyguanosine
Brand Name
Chem Impex
Product Number
00873
CAS
85326-06-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135463029
IUPAC Name
2-amino-9-(2R,5S)-5-(hydroxymethyl)oxolan-2-yl-1H-purin-6-one
InChI Key
OCLZPNCLRLDXJC-NTSWFWBYSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=NC3=C2N=C(NC3=O)N

Application

2',3'-Dideoxyguanosine is widely utilized in research focused on:

Antiviral Drug Development: This compound is a key component in the synthesis of antiviral medications, particularly for treating HIV and hepatitis. Its ability to inhibit viral replication makes it invaluable in pharmaceutical research.

Gene Therapy: Researchers use it to create modified nucleotides for gene therapy applications, helping to develop treatments for genetic disorders by facilitating targeted gene editing.

Biochemical Research: It serves as a crucial tool in studying nucleic acid interactions and enzyme activities, allowing scientists to explore fundamental biological processes.

Diagnostic Tools: The compound is incorporated into diagnostic assays, aiding in the detection of viral infections and genetic mutations, which is essential for personalized medicine.

Comparative Studies: Its unique structure allows for comparative studies with other nucleosides, helping researchers understand the mechanisms of action and resistance in viral pathogens.

References Data Source From Pubchem

Advancing beyond reverse transcriptase inhibitors: The new era of hepatitis B polymerase inhibitors

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2023-09-05
DOI: 10.1016/j.ejmech.2023.115455

Nucleoside Mimetics

Publication Name: Synthesis and Characterization of Glycosides
Publication Date: 2022
DOI: 10.1007/978-3-030-97854-9_4

Impact of the 2′- and 3′-Sugar Hydroxyl Moieties on Gas-Phase Nucleoside Structure

Publication Name: Journal of The American Society for Mass Spectrometry
Publication Date: 2019-03-08
DOI: 10.1007/s13361-019-02155-0

In Vitro Anti-hepatitis B Virus Activity of 2′,3′-Dideoxyguanosine

Publication Name: Virologica Sinica
Publication Date: 2018-11-12
DOI: 10.1007/s12250-018-0065-7

Priming DNA Replication from Triple Helix Oligonucleotides: Possible Threestranded DNA in DNA Polymerases

Publication Name: Molecular Biology International
Publication Date: 2011-09-14
DOI: 10.4061/2011/562849