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Sku CI00407_250_MG
Chem Impex
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Product Information

Product Name
Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers)
Brand Name
Chem Impex
Product Number
00407
CAS
6027-83-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135993863
IUPAC Name
disodium;(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl phosphate
InChI Key
QFYOUTHOUPZZES-LGVAUZIVSA-L
SMILES
C1=NC2=C(N1C@H3C@@H(C@@H(C@H(O3)CO)OP(=O)(O-)O-)O)N=C(NC2=O)N.Na+.Na+

Application

Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is widely utilized in research focused on:

Biochemical Research: This compound serves as a crucial nucleotide in studies related to RNA synthesis and cellular signaling pathways, helping researchers understand genetic expression and regulation.

Pharmaceutical Development: It is used in the formulation of drugs targeting various diseases, particularly those involving metabolic disorders, where modulation of nucleotide levels can be beneficial.

Cell Culture Applications: In cell biology, it acts as a supplement in culture media, enhancing cell growth and viability, which is essential for experiments involving primary cells or stem cells.

Diagnostics: The compound plays a role in developing diagnostic assays, particularly in detecting viral infections, where nucleotide analogs are used to identify viral RNA.

Gene Therapy: It is explored in gene therapy applications, where its role as a nucleotide precursor can aid in the delivery and expression of therapeutic genes in target cells.

References

Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation.

Publication Name: Nature Chemistry
Publication Date: 2013-04-14
DOI: 10.1038/nchem.1626