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Sku CI00523_1_G
Chem Impex
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Product Information

Product Name
N2-Isobutyryl-2'-deoxyguanosine
Brand Name
Chem Impex
Product Number
00523
CAS
68892-42-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135407017
IUPAC Name
N-9-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl-6-oxo-1H-purin-2-yl-2-methylpropanamide
InChI Key
SIDXEQFMTMICKG-DJLDLDEBSA-N
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C@H3CC@@H(C@H(O3)CO)O

Application

N2-Isobutyryl-2'-deoxyguanosine is widely utilized in research focused on:

Antiviral Drug Development: This compound is being explored for its potential in creating antiviral therapies, particularly against viruses that affect the respiratory system, by inhibiting viral replication.

Gene Therapy: It plays a role in gene therapy research, where it can be used to modify nucleic acids, enhancing the delivery and efficacy of therapeutic genes.

Biochemical Research: Researchers use it to study nucleotide metabolism and its implications in various cellular processes, providing insights into cancer and metabolic disorders.

Pharmaceutical Formulations: The compound is being investigated for its use in drug formulations, potentially improving the bioavailability and stability of nucleoside-based drugs.

Diagnostic Tools: It is also being developed for use in diagnostic assays, helping to detect specific nucleic acid sequences associated with diseases, thus aiding in early diagnosis.

References Data Source From Pubchem

A DNA adductome analysis revealed a reduction in the global level of C5-hydroxymethyl-2′-deoxycytidine in the non-tumoral upper urinary tract mucosa of urothelial carcinoma patients

Publication Name: Genes and environment : the official journal of the Japanese Environmental Mutagen Society
Publication Date: 2021-12-02
DOI: 10.1186/s41021-021-00228-9

2′-C,4′-C-Ethyleneoxy-Bridged 2′-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2019
DOI: 10.1007/978-1-4939-9216-4_5