2'-O,4'-C-Methyleneadenosine|CS-0042423|206055-70-1

2'-O,4'-C-Methyleneadenosine

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Sku TS246CS-0042423_250_MG
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Product Information

Product Name
2'-O,4'-C-Methyleneadenosine
Brand Name
ChemScene
Product Number
CS-0042423
CAS
206055-70-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
44436074
IUPAC Name
(1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo2.2.1heptan-7-ol
InChI Key
GHKDRNDFVCEETA-KYAGDKKUSA-N
SMILES
C1C@2(C@H(C@@H(O1)C@@H(O2)N3C=NC4=C(N=CN=C43)N)O)CO

References

An astute synthesis of locked nucleic acid monomers
Publication Name: Sustainable Chemical Processes
Publication Date: 2015-03-04
DOI: 10.1186/s40508-015-0028-3

Synthesis of 2′-O,4′-C-alkylene-bridged ribonucleosides and their evaluation as inhibitors of HCV NS5B polymerase
Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2014-06-15
DOI: 10.1016/j.bmcl.2014.04.050

Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands
Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2007-08-15
DOI: 10.1016/j.bmc.2007.05.056

Synthesis and properties of 2′-O,4′-C-Ethylene-Bridged nucleic acids (ENA) as effective antisense oligonucleotides
Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2003-05-15
DOI: 10.1016/s0968-0896(03)00115-9

CCDC 195963: Experimental Crystal Structure Determination
Publication Date: 2003
DOI: 10.5517/cc6kxd1