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Sku CI00793_1_G
Chem Impex
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Product Information

Product Name
N6-Benzoyl-2'-deoxyadenosine
Brand Name
Chem Impex
Product Number
00793
CAS
4546-72-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
107558
IUPAC Name
N-9-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpurin-6-ylbenzamide
InChI Key
PIXHJAPVPCVZSV-YNEHKIRRSA-N
SMILES
C1C@@H(C@H(OC@H1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

Application

N6-Benzoyl-2'-deoxyadenosine is widely utilized in research focused on

Antiviral Research: This compound is used in the development of antiviral agents, particularly against viruses like HIV. Its structure allows it to interfere with viral replication, making it a valuable tool in drug discovery.

Biochemical Assays: It serves as a substrate in various enzymatic assays, helping researchers study enzyme kinetics and mechanisms. This application is crucial in understanding metabolic pathways and drug interactions.

Gene Therapy: The compound is explored for its potential in gene therapy applications, where it can be used to modify genetic material. Its ability to integrate into nucleic acids makes it a candidate for therapeutic interventions.

Pharmaceutical Development: N6-Benzoyl-2'-deoxyadenosine is investigated for its role in formulating new pharmaceuticals, particularly in oncology, due to its ability to influence cell signaling pathways.

Research on Nucleoside Analogues: It is a key compound in the study of nucleoside analogues, which are essential in developing treatments for various diseases, including cancer and viral infections. Its unique properties offer insights into modifying nucleoside structures for enhanced efficacy.

References Data Source From Pubchem

2′-C,4′-C-Ethyleneoxy-Bridged 2′-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2019
DOI: 10.1007/978-1-4939-9216-4_5

Red light activated “caged” reagents for microRNA research

Publication Name: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Publication Date: 2016-09-01
DOI: 10.1039/c6pp00046k

Nucleophilic Cleavage

Publication Name: Science of Synthesis
Publication Date: 2008

Synthesis of DNA Using a New Two-Step Cycle

Publication Name: Oligonucleotide Synthesis
Publication Date: 2004-08-20
DOI: 10.1385/1-59259-823-4:001

The solid-phase synthesis of 2'-5'-linked oligoriboadenylates containing 8-bromoadenine

Publication Name: Applied Biochemistry and Biotechnology
Publication Date: 1997-07
DOI: 10.1007/bf02787839