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Sku CI00869_250_MG
Chem Impex
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Product Information

Product Name
2',3'-Dideoxyadenosine
Brand Name
Chem Impex
Product Number
00869
CAS
4097-22-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
20039
IUPAC Name
(2S,5R)-5-(6-aminopurin-9-yl)oxolan-2-ylmethanol
InChI Key
WVXRAFOPTSTNLL-NKWVEPMBSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=NC3=C(N=CN=C32)N

Application

2',3'-Dideoxyadenosine is widely utilized in research focused on:

Antiviral Therapy: This compound is primarily used in the development of antiviral drugs, particularly for treating HIV. It acts by inhibiting viral replication, making it a crucial component in antiretroviral therapy.

Research on Nucleoside Analogues: It serves as a valuable tool in studying nucleoside analogues, helping researchers understand their mechanisms and potential therapeutic applications in various viral infections.

Cellular Metabolism Studies: Scientists use this compound to investigate its effects on cellular metabolism and nucleotide synthesis, providing insights into cellular functions and disease mechanisms.

Drug Development: It plays a significant role in the pharmaceutical industry for the design and synthesis of new drugs, particularly those targeting viral infections, due to its unique structural properties.

Biochemical Research: The compound is employed in biochemical assays to study enzyme interactions and pathways, aiding in the discovery of new biological targets for drug development.

References

Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance

Publication Name: Frontiers in Immunology
Publication Date: 2025-06-06
DOI: 10.3389/fimmu.2025.1612451

Development and validation of a graphene quantum dot-based sensor for abacavir quantification via fluorescence quenching

Publication Name: Analytical Biochemistry
Publication Date: 2025-06
DOI: 10.1016/j.ab.2025.115817

Efficacy, Safety and Tolerability of Dispersible and Immediate Release Abacavir/Dolutegravir/Lamivudine Tablets in Children With HIV: IMPAACT 2019 Week 48 Results

Publication Name: The Pediatric infectious disease journal
Publication Date: 2025-05-29
DOI: 10.1097/inf.0000000000004859

A New Method for the Quantification of Ethyl Sulfate and Isopropyl Sulfate Contents in Abacavir Sulfate by Ion Chromatography

Publication Name: Journal of Chromatographic Science
Publication Date: 2025-03-27
DOI: 10.1093/chromsci/bmaf023