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Sku CI00587_10_MG
Chem Impex
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Product Information

Product Name
N6-Methyladenosine-5'-monophosphate sodium salt
Brand Name
Chem Impex
Product Number
00587
CAS
81921-35-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
71299667
IUPAC Name
disodium;(2R,3S,4R,5R)-3,4-dihydroxy-5-6-(methylamino)purin-9-yloxolan-2-ylmethyl phosphate
InChI Key
HFOKUKRAZPHTHH-LYYWGVPGSA-L
SMILES
CNC1=C2C(=NC=N1)N(C=N2)C@H3C@@H(C@@H(C@H(O3)COP(=O)(O-)O-)O)O.Na+.Na+

Application

N6-Methyladenosine-5'-monophosphate sodium salt is widely utilized in research focused on:

RNA Modification Studies: This compound is essential for studying the role of mRNA modifications in gene expression and regulation, providing insights into cellular processes.

Epitranscriptomics: It plays a critical role in epitranscriptomic research, helping scientists understand how RNA modifications affect cellular functions and disease mechanisms.

Drug Development: Researchers use this compound to explore new therapeutic targets in cancer and other diseases, as it can influence RNA stability and translation.

Biotechnology Applications: It is utilized in the development of RNA-based technologies, such as mRNA vaccines, enhancing the efficacy and stability of the RNA used in these applications.

Diagnostics: The compound is valuable in creating diagnostic tools for detecting RNA modifications, which can serve as biomarkers for various diseases.

References Data Source From Pubchem

Multi-region m6A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci

Publication Name: Nature Neuroscience
Publication Date: 2025-12-09
DOI: 10.1038/s41593-025-02112-z

LL22NC03-N14H11.1 regulates the m6A modification of MYC and promotes glycolytic activity in hepatocellular carcinoma cells by inhibiting IGF2BP3 ubiquitination degradation

Publication Name: Journal of experimental & clinical cancer research : CR
Publication Date: 2025-12-02
DOI: 10.1186/s13046-025-03606-1

ALKBH5-mediated RNA N6-methyladenosine demethylation protects against myocardial I/R-induced injury via FSP1-dependent inhibition of ferroptosis

Publication Name: Journal of Molecular Histology
Publication Date: 2025-11-24
DOI: 10.1007/s10735-025-10656-4

METAP2 inhibits K48-linked ubiquitination of YTHDF2 to promote ovarian cancer progression

Publication Name: Oncogene
Publication Date: 2025-10-16
DOI: 10.1038/s41388-025-03594-8

ALKBH5 suppresses m6A mRNA modification of FOXM1 to drive Cetuximab resistance in KRAS-mutant colorectal cancer

Publication Name: Oncogene
Publication Date: 2025-07-07
DOI: 10.1038/s41388-025-03490-1