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Sku CI00869_250_MG
Chem Impex
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Product Information

Product Name
2',3'-Dideoxyadenosine
Brand Name
Chem Impex
Product Number
00869
CAS
4097-22-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
20039
IUPAC Name
(2S,5R)-5-(6-aminopurin-9-yl)oxolan-2-ylmethanol
InChI Key
WVXRAFOPTSTNLL-NKWVEPMBSA-N
SMILES
C1CC@@H(OC@@H1CO)N2C=NC3=C(N=CN=C32)N

Application

2',3'-Dideoxyadenosine is widely utilized in research focused on:

Antiviral Therapy: This compound is primarily used in the development of antiviral drugs, particularly for treating HIV. It acts by inhibiting viral replication, making it a crucial component in antiretroviral therapy.

Research on Nucleoside Analogues: It serves as a valuable tool in studying nucleoside analogues, helping researchers understand their mechanisms and potential therapeutic applications in various viral infections.

Cellular Metabolism Studies: Scientists use this compound to investigate its effects on cellular metabolism and nucleotide synthesis, providing insights into cellular functions and disease mechanisms.

Drug Development: It plays a significant role in the pharmaceutical industry for the design and synthesis of new drugs, particularly those targeting viral infections, due to its unique structural properties.

Biochemical Research: The compound is employed in biochemical assays to study enzyme interactions and pathways, aiding in the discovery of new biological targets for drug development.

References Data Source From Pubchem

Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance

Publication Name: Frontiers in Immunology
Publication Date: 2025-06-06
DOI: 10.3389/fimmu.2025.1612451

Development and validation of a graphene quantum dot-based sensor for abacavir quantification via fluorescence quenching

Publication Name: Analytical Biochemistry
Publication Date: 2025-06
DOI: 10.1016/j.ab.2025.115817

Efficacy, Safety and Tolerability of Dispersible and Immediate Release Abacavir/Dolutegravir/Lamivudine Tablets in Children With HIV: IMPAACT 2019 Week 48 Results

Publication Name: The Pediatric infectious disease journal
Publication Date: 2025-05-29
DOI: 10.1097/inf.0000000000004859

A New Method for the Quantification of Ethyl Sulfate and Isopropyl Sulfate Contents in Abacavir Sulfate by Ion Chromatography

Publication Name: Journal of Chromatographic Science
Publication Date: 2025-03-27
DOI: 10.1093/chromsci/bmaf023